Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BV122_RS05430 Genome accession   NZ_CP020009
Coordinates   1067501..1068175 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 5P54H1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1062501..1073175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV122_RS05395 (BV122_1098) rpmG 1063418..1063588 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BV122_RS05400 (BV122_1099) rpmB 1063600..1063836 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BV122_RS05405 (BV122_1100) radC 1064050..1064715 (-) 666 WP_013526173.1 RadC family protein -
  BV122_RS05410 (BV122_1101) coaBC 1064878..1066080 (+) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BV122_RS05415 (BV122_1102) dut 1066128..1066583 (+) 456 WP_005631431.1 dUTP diphosphatase -
  BV122_RS05420 (BV122_1103) slmA 1066587..1067243 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  BV122_RS05425 (BV122_1104) - 1067265..1067516 (+) 252 WP_005647999.1 YheU family protein -
  BV122_RS05430 (BV122_1105) crp 1067501..1068175 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BV122_RS05435 (BV122_1106) rlmC 1068540..1069721 (-) 1182 WP_042593723.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BV122_RS05440 (BV122_1107) nagZ 1069714..1070769 (-) 1056 WP_105182641.1 beta-N-acetylhexosaminidase -
  BV122_RS05445 (BV122_1108) - 1070773..1071123 (-) 351 WP_005647993.1 YcfL family protein -
  BV122_RS05450 (BV122_1109) hinT 1071123..1071473 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=219883 BV122_RS05430 WP_005647998.1 1067501..1068175(+) (crp) [Haemophilus influenzae strain 5P54H1]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=219883 BV122_RS05430 WP_005647998.1 1067501..1068175(+) (crp) [Haemophilus influenzae strain 5P54H1]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment