Detailed information NTG0219225

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LLG50_RS11160
• Genome accession: NZ_CP025500
• Coordinates: 2269935..2272457 (-)
• Length: 840 a.a.
• NCBI ID: WP_012898701.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain G50
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2264935..2277457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLG50_RS11140 (LLG50_11140)	ruvB	2265192..2266193 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LLG50_RS11145 (LLG50_11145)	ruvA	2266320..2266913 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LLG50_RS11150 (LLG50_11150)	hexB	2267026..2268996 (-)	1971	WP_201261401.1	DNA mismatch repair endonuclease MutL	Machinery gene
LLG50_RS11155 (LLG50_11155)	-	2269125..2269820 (-)	696	WP_023190211.1	hypothetical protein	-
LLG50_RS11160 (LLG50_11160)	hexA	2269935..2272457 (-)	2523	WP_012898701.1	DNA mismatch repair protein MutS	Machinery gene
LLG50_RS11165 (LLG50_11165)	-	2272651..2272998 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
LLG50_RS11170 (LLG50_11170)	-	2273215..2274096 (-)	882	WP_103055188.1	NAD(P)-dependent oxidoreductase	-
LLG50_RS11765	-	2274138..2274344 (-)	207	WP_003132002.1	hypothetical protein	-
LLG50_RS11185 (LLG50_11185)	-	2274703..2275080 (-)	378	WP_003132003.1	DUF1634 domain-containing protein	-
LLG50_RS11190 (LLG50_11190)	-	2275080..2275931 (-)	852	WP_010906392.1	sulfite exporter TauE/SafE family protein	-
LLG50_RS11195 (LLG50_11195)	-	2276117..2276296 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94209.16 Da
• Isoelectric Point: 4.6787

>NTDB_id=219225 LLG50_RS11160 WP_012898701.1 2269935..2272457(-) (hexA) [Lactococcus lactis subsp. lactis strain G50]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=219225 LLG50_RS11160 WP_012898701.1 2269935..2272457(-) (hexA) [Lactococcus lactis subsp. lactis strain G50]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCGGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTA
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCTGAAAATTTACTGATAGATTTATCAGGATTGACCGCCTTAG
AAAATCAAGTCGCTTCAAAATTATTGGCTTATGTTAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCTAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTGCGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGTAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCAGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGACCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCTTTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-784)

• MutS domain I (MutS_I) (7-116)

• MutS domain II (MutS_II) (124-237)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain III (MutS_III) (254-544)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.455	100	0.648
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386