Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CR921_RS06915 Genome accession   NZ_CP025399
Coordinates   1310050..1310694 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain GABA     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1305050..1315694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR921_RS06890 - 1307151..1308149 (-) 999 WP_101415653.1 NAD(P)/FAD-dependent oxidoreductase -
  CR921_RS06895 trmD 1308151..1308870 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  CR921_RS06900 rimM 1308860..1309378 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  CR921_RS06915 vraR 1310050..1310694 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  CR921_RS06920 - 1310684..1311694 (-) 1011 WP_011226288.1 sensor histidine kinase -
  CR921_RS06925 liaF 1311691..1312389 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  CR921_RS10470 - 1312644..1312811 (-) 168 WP_014608530.1 potassium channel family protein -
  CR921_RS06935 stkP/pknB 1313448..1315319 (-) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=218488 CR921_RS06915 WP_002951384.1 1310050..1310694(-) (vraR) [Streptococcus thermophilus strain GABA]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=218488 CR921_RS06915 WP_002951384.1 1310050..1310694(-) (vraR) [Streptococcus thermophilus strain GABA]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment