Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BZ167_RS14475 Genome accession   NZ_CP019626
Coordinates   2965284..2965928 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus sp. 275     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2960284..2970928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZ167_RS14445 (BZ167_14495) - 2960703..2961044 (-) 342 WP_015418107.1 hypothetical protein -
  BZ167_RS14455 (BZ167_14505) degQ 2961507..2961647 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  BZ167_RS14460 (BZ167_14510) - 2961778..2962707 (+) 930 WP_224462816.1 polyprenyl synthetase family protein -
  BZ167_RS14465 (BZ167_14515) comX 2962704..2962874 (+) 171 WP_015418105.1 competence pheromone ComX -
  BZ167_RS14470 (BZ167_14520) comP 2962852..2965203 (+) 2352 WP_015418104.1 histidine kinase Regulator
  BZ167_RS14475 (BZ167_14525) comA 2965284..2965928 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  BZ167_RS14480 (BZ167_14530) - 2965950..2966333 (+) 384 WP_061860832.1 hotdog fold thioesterase -
  BZ167_RS14485 (BZ167_14535) mnhG 2966373..2966747 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  BZ167_RS14490 (BZ167_14540) - 2966731..2967015 (-) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  BZ167_RS14495 (BZ167_14545) - 2967015..2967491 (-) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  BZ167_RS14500 (BZ167_14550) - 2967497..2968984 (-) 1488 WP_032867186.1 Na+/H+ antiporter subunit D -
  BZ167_RS14505 (BZ167_14555) - 2968977..2969318 (-) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  BZ167_RS14510 (BZ167_14560) - 2969318..2969749 (-) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=217370 BZ167_RS14475 WP_003152052.1 2965284..2965928(+) (comA) [Bacillus sp. 275]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=217370 BZ167_RS14475 WP_003152052.1 2965284..2965928(+) (comA) [Bacillus sp. 275]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGACGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGACAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment