Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CWI26_RS02655 Genome accession   NZ_CP025043
Coordinates   525882..526523 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain AH681     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 520882..531523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS12445 - 521738..522202 (+) 465 Protein_465 PASTA domain-containing protein -
  CWI26_RS02640 (CWI26_02640) - 522536..523657 (+) 1122 WP_100881187.1 IS110 family transposase -
  CWI26_RS02645 (CWI26_02645) liaF 524202..524897 (+) 696 WP_024377219.1 cell wall-active antibiotics response protein LiaF -
  CWI26_RS02650 (CWI26_02650) - 524894..525910 (+) 1017 WP_024419556.1 sensor histidine kinase -
  CWI26_RS02655 (CWI26_02655) vraR 525882..526523 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  CWI26_RS02660 (CWI26_02660) - 526573..527973 (+) 1401 WP_029173958.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  CWI26_RS02665 (CWI26_02665) - 527975..528346 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  CWI26_RS02670 (CWI26_02670) cysK 528372..529298 (-) 927 WP_029185780.1 cysteine synthase A -
  CWI26_RS02675 (CWI26_02675) - 529388..530020 (-) 633 WP_024419558.1 YigZ family protein -
  CWI26_RS02680 (CWI26_02680) comFA/cflA 530077..531369 (+) 1293 WP_024377223.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=216595 CWI26_RS02655 WP_002937025.1 525882..526523(+) (vraR) [Streptococcus suis strain AH681]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=216595 CWI26_RS02655 WP_002937025.1 525882..526523(+) (vraR) [Streptococcus suis strain AH681]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCTCTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment