Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   BWR56_RS08335 Genome accession   NZ_CP019562
Coordinates   1698249..1699073 (-) Length   274 a.a.
NCBI ID   WP_061587302.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1693249..1704073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS08320 (BWR56_1650) amiA 1694300..1696279 (-) 1980 WP_076984802.1 peptide ABC transporter substrate-binding protein Regulator
  BWR56_RS08330 (BWR56_1652) - 1696782..1698113 (-) 1332 WP_076984803.1 hemolysin family protein -
  BWR56_RS08335 (BWR56_1653) endA 1698249..1699073 (-) 825 WP_061587302.1 DNA/RNA non-specific endonuclease Machinery gene
  BWR56_RS08340 (BWR56_1654) - 1699114..1699308 (-) 195 WP_000739700.1 DNA-directed RNA polymerase subunit beta -
  BWR56_RS08345 (BWR56_1655) murA 1699295..1700578 (-) 1284 WP_033629306.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  BWR56_RS08350 - 1700602..1700832 (-) 231 WP_076984804.1 DUF1146 family protein -
  BWR56_RS08355 (BWR56_1656) sepM 1700888..1701925 (-) 1038 WP_049501597.1 SepM family pheromone-processing serine protease Regulator
  BWR56_RS08360 (BWR56_1657) coaD 1701909..1702397 (-) 489 WP_076984805.1 pantetheine-phosphate adenylyltransferase -
  BWR56_RS08365 (BWR56_1658) rsmD 1702387..1702926 (-) 540 WP_000706943.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  BWR56_RS08370 (BWR56_1659) asnA 1702991..1703983 (-) 993 WP_000747998.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29915.54 Da        Isoelectric Point: 9.7190

>NTDB_id=216341 BWR56_RS08335 WP_061587302.1 1698249..1699073(-) (endA) [Streptococcus oralis strain S.MIT/ORALIS-351]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTESIKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYQTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=216341 BWR56_RS08335 WP_061587302.1 1698249..1699073(-) (endA) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTACATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTGG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAATCAAATCAAGGGGGGGCTCGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCCAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAGACTGGAAATGGCT
CAACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAGCCTACACACATGCAGTTGATAGAGGACAT
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAATATTGCAGTTCAGAC
GGCTTGGGCAAACCAAGCACAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAATAAGAGAGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACTTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCAAAC
GGGTCAAGTAACAGTGACGGACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.011

99.635

0.887
  endA Streptococcus pneumoniae D39

89.011

99.635

0.887
  endA Streptococcus pneumoniae R6

89.011

99.635

0.887
  endA Streptococcus pneumoniae TIGR4

89.011

99.635

0.887

Multiple sequence alignment