Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BWR56_RS01660 Genome accession   NZ_CP019562
Coordinates   354776..355465 (+) Length   229 a.a.
NCBI ID   WP_007520625.1    Uniprot ID   A0A1X1GGK8
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 349776..360465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS01635 (BWR56_0318) gpsB 349837..350166 (+) 330 WP_000146523.1 cell division regulator GpsB -
  BWR56_RS01645 (BWR56_0319) - 350652..351809 (+) 1158 WP_000662902.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  BWR56_RS01650 (BWR56_0320) mapZ 351822..353264 (+) 1443 WP_076984326.1 cell division site-positioning protein MapZ -
  BWR56_RS01655 (BWR56_0321) gndA 353340..354764 (+) 1425 WP_076984327.1 NADP-dependent phosphogluconate dehydrogenase -
  BWR56_RS01660 (BWR56_0322) covR 354776..355465 (+) 690 WP_007520625.1 response regulator transcription factor Regulator
  BWR56_RS01665 (BWR56_0323) cbpJ 355565..356572 (+) 1008 WP_076984328.1 choline-binding protein CbpJ -
  BWR56_RS01670 (BWR56_0324) cbpC 356590..357609 (+) 1020 WP_076984329.1 choline-binding protein CbpC -
  BWR56_RS01675 (BWR56_0325) mvk 357727..358605 (+) 879 WP_076984330.1 mevalonate kinase -
  BWR56_RS01680 (BWR56_0326) mvaD 358587..359540 (+) 954 WP_076984331.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26812.97 Da        Isoelectric Point: 8.0271

>NTDB_id=216307 BWR56_RS01660 WP_007520625.1 354776..355465(+) (covR) [Streptococcus oralis strain S.MIT/ORALIS-351]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=216307 BWR56_RS01660 WP_007520625.1 354776..355465(+) (covR) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCGGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATAATCTAGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATTGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAACCTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCAACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GGK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment