Detailed information NTG0021627

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NMA_RS01535
• Genome accession: NC_003116
• Coordinates: 276314..277579 (+)
• Length: 421 a.a.
• NCBI ID: WP_002247114.1
• Uniprot ID: P57010
• Organism: Neisseria meningitidis Z2491
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 271314..282579

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMA_RS01515 (NMA0287)	-	272044..273045 (+)	1002	WP_002220087.1	thiamine ABC transporter substrate-binding protein	-
NMA_RS01520 (NMA0288)	-	273139..273987 (+)	849	WP_002218471.1	mechanosensitive ion channel family protein	-
NMA_RS01525 (NMA0289)	-	274013..274498 (+)	486	WP_002215245.1	CinA family protein	-
NMA_RS01530 (NMA0290)	msrAB	274600..276168 (-)	1569	WP_002216163.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NMA_RS01535 (NMA0291)	pilA	276314..277579 (+)	1266	WP_002247114.1	signal recognition particle-docking protein FtsY	Machinery gene
NMA_RS01540 (NMA0292)	-	278168..278452 (+)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
NMA_RS14895	pilC	279084..279215 (+)	132	WP_306808038.1	hypothetical protein	Machinery gene
NMA_RS01545 (NMA0293)	pilC	279185..282250 (+)	3066	Protein_282	PilC family type IV pilus tip adhesin	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45115.41 Da
• Isoelectric Point: 4.5557

>NTDB_id=21627 NMA_RS01535 WP_002247114.1 276314..277579(+) (pilA) [Neisseria meningitidis Z2491]
MFSFFRRKKKQETPALEEAQIQETAAKAESETAQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKEAVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=21627 NMA_RS01535 WP_002247114.1 276314..277579(+) (pilA) [Neisseria meningitidis Z2491]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGCTCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAGCCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTAGAGAAACCGCTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACATCCATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTTACCGTGATTTCGCAAACCACAGGCGATTCCGCCGCCGTTTGTTTTGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

• SRP54-type protein, GTPase domain (SRP54) (221-420)

3D structure

• AlphaFold DB: P57010

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.824	100	0.938