Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BZG42_RS07500 Genome accession   NZ_CP019557
Coordinates   1585925..1586614 (-) Length   229 a.a.
NCBI ID   WP_024532842.1    Uniprot ID   A0A2Z5TS70
Organism   Streptococcus sp. DAT741     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1580925..1591614
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS07475 (BZG42_07545) - 1581020..1581733 (-) 714 WP_165437179.1 nitroreductase family protein -
  BZG42_RS07480 (BZG42_07550) dnaI 1581730..1582629 (-) 900 WP_024532838.1 primosomal protein DnaI -
  BZG42_RS07485 (BZG42_07555) - 1582629..1583777 (-) 1149 WP_155964995.1 replication initiation/membrane attachment protein -
  BZG42_RS07490 (BZG42_07560) nrdR 1583782..1584255 (-) 474 WP_024532840.1 transcriptional regulator NrdR -
  BZG42_RS07495 (BZG42_07565) - 1584328..1585458 (-) 1131 WP_024532841.1 AI-2E family transporter -
  BZG42_RS07500 (BZG42_07570) covR 1585925..1586614 (-) 690 WP_024532842.1 winged helix-turn-helix domain-containing protein Regulator
  BZG42_RS07505 (BZG42_07575) gndA 1587046..1588473 (-) 1428 WP_155996375.1 NADP-dependent phosphogluconate dehydrogenase -
  BZG42_RS07510 (BZG42_07580) - 1588764..1589312 (-) 549 WP_155964255.1 YceD family protein -
  BZG42_RS07515 (BZG42_07585) trxB 1589322..1590239 (-) 918 WP_120172054.1 thioredoxin-disulfide reductase -
  BZG42_RS07520 (BZG42_07590) - 1590253..1590477 (-) 225 WP_120172055.1 DUF4059 family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26184.11 Da        Isoelectric Point: 5.9622

>NTDB_id=216230 BZG42_RS07500 WP_024532842.1 1585925..1586614(-) (covR) [Streptococcus sp. DAT741]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYVSTGKEALSLAHETDFDLILMSFQLSDMSSKELAKELLAMKPATVMIVA
MDPADVSQHGEEVLAYAVSYVVKPFVISDLVEQISAIFRGRDFIDNHCKQVHLHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEAVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPNQESYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=216230 BZG42_RS07500 WP_024532842.1 1585925..1586614(-) (covR) [Streptococcus sp. DAT741]
ATGGCTAAGAAAATTTTGATTGCTGGAAAAGAGCGCAATCTATCGCATTTTGTTTCTATGGAATTGCAAAAAAAGGATTA
CCTTGTGGACTATGTGTCAACCGGAAAGGAAGCCCTGTCTTTGGCTCATGAAACAGATTTTGACTTAATTCTGATGAGTT
TTCAGCTATCAGATATGTCTAGTAAGGAATTAGCCAAGGAGTTGCTGGCAATGAAGCCTGCAACGGTCATGATTGTAGCA
ATGGATCCTGCGGATGTGTCCCAGCATGGTGAGGAAGTATTGGCCTATGCTGTATCCTATGTGGTGAAACCTTTTGTTAT
CAGTGACTTGGTAGAGCAAATTTCCGCTATTTTTCGTGGTCGAGACTTTATTGATAATCACTGCAAGCAGGTTCATTTGC
ACGCTGCTTATCGGGATTTAAAGGTTGATTTTCAAAATCGGACGGTAACGCGTGGGGATGAGTTAATCAATCTAACCCGC
CGTGAATACGATTTACTAGCAACCTTGATGAATAGTCCTGAAGCGGTCAGTCGGGAGCAGCTCTTAGAGCGAGTTTGGAA
ATATGAAGCTGCCTCTGAAACGAATGTAGTAGATGTTTATATTCGTTATTTACGAGGGAAATTAGACTTACCCAATCAGG
AGTCTTATATCAAAACAGTTCGCGGTGTTGGCTATGCCATGCGTGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TS70

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.305

100

0.498
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

100

0.441

Multiple sequence alignment