Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   BZG42_RS05065 Genome accession   NZ_CP019557
Coordinates   1046322..1047548 (-) Length   408 a.a.
NCBI ID   WP_024532031.1    Uniprot ID   A0A2Z5TMW9
Organism   Streptococcus sp. DAT741     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041322..1052548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS05045 (BZG42_05095) - 1041927..1043243 (-) 1317 WP_155996407.1 excalibur calcium-binding domain-containing protein -
  BZG42_RS05050 (BZG42_05100) - 1043376..1043558 (+) 183 WP_120171717.1 4-oxalocrotonate tautomerase -
  BZG42_RS05055 (BZG42_05105) lepA 1043632..1045464 (-) 1833 WP_024532033.1 translation elongation factor 4 -
  BZG42_RS05060 (BZG42_05110) yihA 1045675..1046262 (-) 588 WP_155972984.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  BZG42_RS05065 (BZG42_05115) clpX 1046322..1047548 (-) 1227 WP_024532031.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  BZG42_RS05075 (BZG42_05125) - 1047748..1048260 (-) 513 WP_120171718.1 dihydrofolate reductase -
  BZG42_RS05080 (BZG42_05130) - 1048672..1049511 (-) 840 WP_024532029.1 thymidylate synthase -
  BZG42_RS05085 (BZG42_05135) - 1049563..1049760 (-) 198 WP_120171719.1 hypothetical protein -
  BZG42_RS05090 (BZG42_05140) - 1049773..1050051 (-) 279 WP_024532027.1 hypothetical protein -
  BZG42_RS05095 (BZG42_05145) - 1050175..1051134 (-) 960 WP_120171720.1 ROK family glucokinase -
  BZG42_RS05100 (BZG42_05150) - 1051337..1051672 (-) 336 WP_155996405.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45410.93 Da        Isoelectric Point: 4.6108

>NTDB_id=216225 BZG42_RS05065 WP_024532031.1 1046322..1047548(-) (clpX) [Streptococcus sp. DAT741]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDDNDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLIRIL
TEPKNALVKQYQTLLSYDDVELEFDEDALEEIAKKAIERKTGARGLRSIIEETMLDVMFEVPGQDEVKRVRVTKAAVNGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=216225 BZG42_RS05065 WP_024532031.1 1046322..1047548(-) (clpX) [Streptococcus sp. DAT741]
ATGGCTGTTAAGCATACACATGAGCTTATTTACTGCTCATTTTGTGGAAAAAATCAAGAAGAAGTCAAAAAAATTATTGC
CGGAAACAATGTATTTATCTGTAATGAATGTGTCGAATTAGCACAAGAAATCATTCGTGAGGAATTGGCAGAAGAAGTTC
TAACAGACTTGGCTGATACGCCAAAACCACAGGAATTATTAAATATCCTAAACAACTATGTCATCGGACAAGACCGGGCG
AAACGTGCGCTGGCAGTGGCGGTTTATAACCACTATAAACGAATCAATTTTCAAGACAGTCGTGATGATAATGATGTTGA
TTTACAAAAATCAAATATCCTCATGATTGGACCAACTGGATCTGGTAAAACCTTCTTAGCACAGACTCTCGCTAAAAGTT
TGAATGTGCCATTTGCGATTGCAGATGCCACAGCCTTGACAGAAGCAGGTTATGTTGGTGAGGATGTAGAAAATATCCTT
CTCAAACTCTTGCAGGCGGCAGATTTCAATATTGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACGCGGGATGTATCCGGTGAAGGTGTTCAGCAGGCTCTCCTAAAAATTATCG
AGGGGACAGTTGCTAGCGTACCACCACAGGGAGGACGTAAACATCCAAACCAAGAGATGATCCATGTAGACACCAAGAAC
ATCCTCTTCATCGTAGGTGGTGCTTTTGATGGTATTGAGGAAATTGTTAAACAACGTCTCGGCGAAAAAATTATTGGATT
TGGTCAGAATAATCGTGCCATTGATGAAAAAGAATCCTACATGCAACATATTATCGCTGATGATATTCAAAAATTTGGTA
TCATTCCAGAATTGATTGGTCGTTTACCAGTTTTTGCAGCTCTGGATCAACTGACAACAGAGGATTTGATTCGCATTCTG
ACTGAACCTAAAAATGCTCTGGTGAAGCAATACCAAACGCTCCTTTCGTACGATGATGTGGAATTAGAATTTGACGAGGA
TGCCTTGGAGGAAATTGCTAAAAAAGCAATTGAGCGTAAAACAGGTGCTCGTGGTCTTCGCTCCATTATTGAGGAAACAA
TGCTGGATGTCATGTTTGAAGTGCCGGGTCAAGATGAGGTTAAGCGTGTTCGAGTAACCAAAGCTGCAGTAAATGGCAAG
GAAAAGCCACTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TMW9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.374

100

0.836
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.96

98.529

0.571

Multiple sequence alignment