Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BZG42_RS04690 Genome accession   NZ_CP019557
Coordinates   973709..974446 (+) Length   245 a.a.
NCBI ID   WP_155996443.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 968709..979446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS04675 (BZG42_04705) - 968951..970219 (+) 1269 WP_155996447.1 dihydroorotase -
  BZG42_RS04680 (BZG42_04710) nt5e 970352..972421 (+) 2070 WP_155996445.1 cell surface ecto-5'-nucleotidase Nt5e -
  BZG42_RS04690 (BZG42_04725) comE/blpR 973709..974446 (+) 738 WP_155996443.1 response regulator transcription factor Regulator
  BZG42_RS10090 - 974460..975317 (+) 858 WP_227985528.1 hypothetical protein -
  BZG42_RS10095 - 975357..975800 (+) 444 WP_227985529.1 GHKL domain-containing protein -
  BZG42_RS04700 (BZG42_04735) - 975857..975982 (-) 126 WP_079276156.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BZG42_RS04705 (BZG42_04740) - 976273..976527 (+) 255 WP_155996441.1 Blp family class II bacteriocin -
  BZG42_RS04710 (BZG42_04745) - 976543..976749 (+) 207 WP_155962947.1 Blp family class II bacteriocin -
  BZG42_RS04715 (BZG42_04755) - 977297..977530 (+) 234 WP_155973059.1 bacteriocin class II family protein -
  BZG42_RS04720 (BZG42_04760) - 977748..977981 (+) 234 WP_155970572.1 bacteriocin class II family protein -
  BZG42_RS04725 (BZG42_04765) - 978199..978432 (+) 234 WP_155973056.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BZG42_RS04730 (BZG42_04770) - 978432..978743 (+) 312 WP_162496986.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28548.04 Da        Isoelectric Point: 7.1060

>NTDB_id=216223 BZG42_RS04690 WP_155996443.1 973709..974446(+) (comE/blpR) [Streptococcus sp. DAT741]
MNIFVLEDDIIQQTRIEKVLNNLLEKHKIEPKKLIISGKPEQLIASVEEKGAHQLFFLDIEIRSEELKGLKVAKQIRDID
PYAIIIFVTTHSEFMPLSFRYQVSALDYIEKELATREFESRIETALLYAVSKDSKTVAEDSFYFKSKYAQVQYPFDEVYY
VETSPRPHRVILYTRTDCMEFTASLSDILKQEKRLVQCHRSFLINPANVIKIDRQAKVVYFPNGTHCLVARKKLDVTLAT
IDQLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=216223 BZG42_RS04690 WP_155996443.1 973709..974446(+) (comE/blpR) [Streptococcus sp. DAT741]
ATGAATATATTTGTACTAGAAGATGATATTATACAACAAACAAGGATTGAAAAAGTGCTTAACAATCTTTTGGAGAAACA
TAAAATAGAGCCCAAAAAACTTATAATTTCTGGGAAACCCGAACAGTTGATTGCTTCAGTGGAGGAGAAAGGGGCGCACC
AGTTGTTCTTTTTGGATATTGAGATAAGATCAGAAGAACTTAAAGGTCTTAAAGTCGCTAAACAAATCAGAGATATTGAT
CCTTATGCTATTATTATTTTTGTGACGACGCATTCTGAATTTATGCCTCTCTCTTTTCGTTATCAAGTATCAGCATTAGA
TTATATTGAGAAGGAACTAGCAACGAGAGAATTTGAATCTCGCATAGAAACAGCTTTACTGTATGCAGTGAGTAAAGATA
GTAAAACAGTAGCTGAGGATTCTTTCTATTTCAAATCTAAATATGCCCAAGTTCAGTACCCATTTGATGAAGTTTACTAT
GTTGAAACGTCTCCAAGACCACATAGGGTTATCCTTTATACAAGAACTGATTGTATGGAGTTCACCGCCAGTTTATCAGA
TATTTTAAAGCAAGAAAAGAGACTGGTACAGTGTCATCGTTCGTTTCTTATCAATCCTGCAAATGTTATCAAAATAGATA
GACAAGCCAAAGTTGTTTATTTTCCCAATGGGACACATTGTTTGGTTGCAAGAAAAAAATTAGATGTTACTTTGGCGACT
ATAGACCAGTTGCACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-234)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.066

98.776

0.514
  comE/comE1 Streptococcus equinus JB1

41.423

97.551

0.404

Multiple sequence alignment