Detailed information NTG0021622

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: NMA_RS01080
• Genome accession: NC_003116
• Coordinates: 194074..194538 (-)
• Length: 154 a.a.
• NCBI ID: WP_010981060.1
• Uniprot ID: -
• Organism: Neisseria meningitidis Z2491
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	174999..200754	194074..194538	within	0

Gene organization within MGE regions

Location: 174999..200754

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMA_RS00995 (NMA0193)	-	174999..175829 (-)	831	WP_002215283.1	DNA cytosine methyltransferase	-
NMA_RS01000 (NMA0194)	-	175860..178133 (-)	2274	WP_002239407.1	Tex family protein	-
NMA_RS01005 (NMA0195)	-	178197..178847 (-)	651	WP_002218516.1	ABC transporter ATP-binding protein	-
NMA_RS01010 (NMA0196)	-	178844..179641 (-)	798	WP_002236582.1	ABC transporter permease	-
NMA_RS01015 (NMA0197)	-	179641..180804 (-)	1164	WP_002236581.1	capsule polysaccharide export inner-membrane protein CtrB	-
NMA_RS01020 (NMA0198)	ctrA	180819..181982 (-)	1164	WP_002236580.1	capsule polysaccharide export outer membrane protein CtrA	-
NMA_RS01025 (NMA0199)	wecB	182201..183319 (+)	1119	WP_002236579.1	non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase	-
NMA_RS01030 (NMA0200)	-	183321..184958 (+)	1638	WP_002236578.1	stealth family protein	-
NMA_RS01035 (NMA0201)	-	185031..185774 (+)	744	WP_002236577.1	YqiA/YcfP family alpha/beta fold hydrolase	-
NMA_RS01040 (NMA0202)	-	185776..186639 (+)	864	WP_002236576.1	galactosyltransferase-related protein	-
NMA_RS01045 (NMA0203)	galE	186684..187703 (+)	1020	WP_002249820.1	UDP-glucose 4-epimerase GalE	-
NMA_RS01050 (NMA0204)	rfbB	187819..188844 (+)	1026	WP_002236574.1	dTDP-glucose 4,6-dehydratase	-
NMA_RS01055 (NMA0205)	rfbA	188950..189816 (+)	867	WP_010981057.1	glucose-1-phosphate thymidylyltransferase RfbA	-
NMA_RS01060 (NMA0206)	rfbC	189870..190427 (+)	558	WP_002246730.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
NMA_RS01065 (NMA0207)	-	190470..192488 (-)	2019	WP_002236572.1	OPT family oligopeptide transporter	-
NMA_RS01070 (NMA0209)	dnaJ	192683..193804 (-)	1122	WP_002215274.1	molecular chaperone DnaJ	-
NMA_RS01080 (NMA0211)	comE	194074..194538 (-)	465	WP_010981060.1	ComEA family DNA-binding protein	Machinery gene
NMA_RS01115 (NMA0213)	dksA	200338..200754 (-)	417	WP_002231430.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16529.75 Da
• Isoelectric Point: 10.6993

>NTDB_id=21622 NMA_RS01080 WP_010981060.1 194074..194538(-) (comE) [Neisseria meningitidis Z2491]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide

• Length: 465 bp

>NTDB_id=21622 NMA_RS01080 WP_010981060.1 194074..194538(-) (comE) [Neisseria meningitidis Z2491]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGTGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	94.262	79.221	0.747
comE	Neisseria gonorrhoeae MS11	94.262	79.221	0.747
comE	Neisseria gonorrhoeae MS11	94.262	79.221	0.747
comE	Neisseria gonorrhoeae MS11	94.262	79.221	0.747