Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | BZG33_RS03325 | Genome accession | NZ_CP019466 |
| Coordinates | 562714..563376 (+) | Length | 220 a.a. |
| NCBI ID | WP_047916986.1 | Uniprot ID | A0AA44U7R7 |
| Organism | Neisseria gonorrhoeae strain RIVM0610 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 561054..604401 | 562714..563376 | within | 0 |
Gene organization within MGE regions
Location: 561054..604401
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BZG33_RS03320 (BZG33_03260) | dnaB | 561054..562457 (+) | 1404 | WP_012503477.1 | replicative DNA helicase | - |
| BZG33_RS03325 (BZG33_03265) | pilH | 562714..563376 (+) | 663 | WP_047916986.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| BZG33_RS03330 (BZG33_03270) | pilI | 563408..564022 (+) | 615 | WP_012503479.1 | type IV pilus modification protein PilV | Machinery gene |
| BZG33_RS03335 (BZG33_03275) | pilJ | 564019..564981 (+) | 963 | WP_047921846.1 | PilW family protein | Machinery gene |
| BZG33_RS03340 (BZG33_03280) | pilK | 564960..565568 (+) | 609 | WP_047921847.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| BZG33_RS03345 (BZG33_03285) | pilL | 565570..566043 (+) | 474 | WP_012503482.1 | PilX family type IV pilin | Machinery gene |
| BZG33_RS03350 (BZG33_03290) | - | 566113..566421 (-) | 309 | WP_003706588.1 | AzlD family protein | - |
| BZG33_RS03355 (BZG33_03295) | - | 566418..567129 (-) | 712 | Protein_562 | AzlC family ABC transporter permease | - |
| BZG33_RS03360 (BZG33_03300) | dut | 567295..567747 (+) | 453 | WP_003701071.1 | dUTP diphosphatase | - |
| BZG33_RS03365 (BZG33_03305) | dapC | 567819..569006 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| BZG33_RS03370 (BZG33_03310) | yaaA | 569162..569941 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| BZG33_RS03385 (BZG33_03325) | - | 570471..571671 (+) | 1201 | Protein_566 | tyrosine-type recombinase/integrase | - |
| BZG33_RS03400 (BZG33_03335) | - | 572027..572296 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| BZG33_RS03405 (BZG33_03340) | - | 572491..573174 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| BZG33_RS14580 | - | 573488..573721 (-) | 234 | Protein_569 | hypothetical protein | - |
| BZG33_RS03415 (BZG33_03350) | - | 573832..574047 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| BZG33_RS03420 (BZG33_03355) | - | 574099..574590 (-) | 492 | WP_047916888.1 | siphovirus Gp157 family protein | - |
| BZG33_RS03425 (BZG33_03360) | - | 574587..574769 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| BZG33_RS03430 (BZG33_03365) | - | 574909..575595 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| BZG33_RS03435 (BZG33_03370) | - | 575664..575825 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| BZG33_RS03440 (BZG33_03375) | - | 575822..576100 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| BZG33_RS03445 (BZG33_03380) | - | 576253..576585 (-) | 333 | WP_003705604.1 | hypothetical protein | - |
| BZG33_RS03450 (BZG33_03385) | - | 576726..577013 (-) | 288 | WP_041421246.1 | hypothetical protein | - |
| BZG33_RS03455 (BZG33_03390) | - | 577010..577486 (-) | 477 | WP_002255718.1 | hypothetical protein | - |
| BZG33_RS03460 (BZG33_03395) | - | 577519..577719 (-) | 201 | WP_047920246.1 | hypothetical protein | - |
| BZG33_RS03465 (BZG33_03400) | - | 578203..578421 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| BZG33_RS03470 (BZG33_03405) | - | 578438..578797 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| BZG33_RS03475 (BZG33_03410) | - | 578798..579337 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| BZG33_RS03480 (BZG33_03415) | - | 579497..580213 (-) | 717 | WP_003695999.1 | helix-turn-helix transcriptional regulator | - |
| BZG33_RS03490 (BZG33_03425) | - | 580594..580821 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| BZG33_RS03495 (BZG33_03430) | - | 580939..582003 (+) | 1065 | WP_050154181.1 | hypothetical protein | - |
| BZG33_RS03500 (BZG33_03435) | - | 582000..583361 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| BZG33_RS03505 (BZG33_03440) | - | 583398..583661 (+) | 264 | WP_154235845.1 | hypothetical protein | - |
| BZG33_RS03510 (BZG33_03445) | - | 583700..584194 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| BZG33_RS03515 (BZG33_03450) | - | 584371..584520 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| BZG33_RS14085 | - | 584549..584830 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| BZG33_RS03520 (BZG33_03455) | - | 584821..585258 (+) | 438 | WP_047918627.1 | RusA family crossover junction endodeoxyribonuclease | - |
| BZG33_RS03525 (BZG33_03460) | - | 585251..585556 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| BZG33_RS03530 (BZG33_03465) | - | 585553..585936 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| BZG33_RS03535 (BZG33_03470) | - | 585927..586445 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| BZG33_RS03540 (BZG33_03475) | - | 586510..586932 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| BZG33_RS14090 | - | 586932..587471 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| BZG33_RS03555 (BZG33_03490) | - | 587452..588726 (+) | 1275 | WP_003701186.1 | PBSX family phage terminase large subunit | - |
| BZG33_RS03560 (BZG33_03495) | - | 588711..590978 (+) | 2268 | WP_229689248.1 | hypothetical protein | - |
| BZG33_RS03565 (BZG33_03500) | - | 591215..592411 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| BZG33_RS03570 (BZG33_03505) | - | 592408..593847 (+) | 1440 | WP_050153730.1 | hypothetical protein | - |
| BZG33_RS14095 | - | 596538..599642 (+) | 3105 | Protein_601 | PLxRFG domain-containing protein | - |
| BZG33_RS14100 (BZG33_03515) | - | 599624..600361 (+) | 738 | WP_003690932.1 | hypothetical protein | - |
| BZG33_RS03585 (BZG33_03520) | - | 600382..601677 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| BZG33_RS03590 (BZG33_03525) | - | 601732..602205 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| BZG33_RS03595 (BZG33_03530) | - | 602211..602696 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| BZG33_RS03600 (BZG33_03535) | - | 602693..603367 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| BZG33_RS03605 (BZG33_03540) | - | 603370..603519 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| BZG33_RS03610 (BZG33_03545) | - | 603556..604401 (-) | 846 | WP_047921371.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 220 a.a. Molecular weight: 24557.00 Da Isoelectric Point: 9.6166
>NTDB_id=215960 BZG33_RS03325 WP_047916986.1 562714..563376(+) (pilH) [Neisseria gonorrhoeae strain RIVM0610]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNFKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNFKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
Nucleotide
Download Length: 663 bp
>NTDB_id=215960 BZG33_RS03325 WP_047916986.1 562714..563376(+) (pilH) [Neisseria gonorrhoeae strain RIVM0610]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTTCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTTCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
95.455 |
100 |
0.955 |