Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CVT30_RS42100 Genome accession   NZ_CP024989
Coordinates   9568603..9569268 (+) Length   221 a.a.
NCBI ID   WP_093790595.1    Uniprot ID   A0ABU4MUN8
Organism   Streptomyces sp. AMCC400023     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9563603..9574268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVT30_RS42080 (CVT30_42405) - 9564722..9565927 (+) 1206 WP_045561749.1 geranylgeranyl reductase family protein -
  CVT30_RS42085 (CVT30_42410) - 9565977..9566429 (-) 453 WP_045561750.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  CVT30_RS42090 (CVT30_42415) - 9566586..9567290 (+) 705 WP_093790597.1 TetR/AcrR family transcriptional regulator -
  CVT30_RS42095 (CVT30_42420) - 9567350..9568606 (+) 1257 WP_237311680.1 histidine kinase -
  CVT30_RS42100 (CVT30_42425) vraR 9568603..9569268 (+) 666 WP_093790595.1 response regulator transcription factor Regulator
  CVT30_RS42105 (CVT30_42430) - 9569229..9569552 (-) 324 WP_045561754.1 DUF6332 family protein -
  CVT30_RS42110 (CVT30_42435) - 9569616..9570380 (-) 765 WP_045561755.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  CVT30_RS42115 (CVT30_42440) tgmB 9570552..9571535 (-) 984 WP_045561756.1 ATP-grasp ribosomal peptide maturase -
  CVT30_RS42120 (CVT30_42445) tgmA 9571552..9571743 (-) 192 WP_033525738.1 putative ATP-grasp-modified RiPP -
  CVT30_RS42125 (CVT30_42450) - 9571923..9573197 (-) 1275 WP_237311682.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23909.66 Da        Isoelectric Point: 4.7106

>NTDB_id=215944 CVT30_RS42100 WP_093790595.1 9568603..9569268(+) (vraR) [Streptomyces sp. AMCC400023]
MIRVLLADDQALVRAGFRALLDAQPDIEVAGEAADGEEALRGVRELRPDVVLMDIRMPLLDGLAATRRITDDPGLAGVKV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELVRAVRAVVEGDALLSPGVTRRLIAEFAARSKEPSALSSLDGLTERER
EVMALVGIGLTNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=215944 CVT30_RS42100 WP_093790595.1 9568603..9569268(+) (vraR) [Streptomyces sp. AMCC400023]
GTGATCCGCGTACTGCTGGCCGACGACCAGGCGCTGGTGAGGGCCGGGTTCAGGGCGCTGCTCGACGCGCAGCCCGACAT
CGAGGTGGCCGGGGAGGCCGCCGACGGCGAGGAGGCACTGCGCGGCGTGCGTGAACTCCGCCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCCTGCTCGACGGGCTCGCCGCGACACGGCGCATCACCGACGACCCCGGCCTGGCCGGGGTGAAGGTC
GTCATGCTGACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCCATCCGTGCCGGCGCGTCAGGCTTTCTGGTCAAGGA
CACCGAACCCGAGGAACTCGTGCGCGCGGTACGGGCGGTGGTCGAGGGCGACGCGCTGCTGTCGCCCGGTGTGACCCGGC
GGCTGATCGCCGAGTTCGCCGCCCGGTCCAAGGAGCCCTCGGCCCTCTCCTCGCTCGACGGACTGACCGAGCGGGAACGG
GAGGTGATGGCTCTGGTCGGTATCGGTCTGACCAACGAGGAGATCGCCCGCCGGCTCGTCGTCAGTCCGCTCACGGCCAA
GACGCACGTCAGCCGCACGATGGTGAAGCTGGGCGCCCGCGACCGCGCCCAACTCGTCGTCCTCGCCTACGAGTCCGGGT
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367