Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CVT30_RS30585 Genome accession   NZ_CP024989
Coordinates   6939334..6939993 (-) Length   219 a.a.
NCBI ID   WP_045557403.1    Uniprot ID   A0ABU4MVW0
Organism   Streptomyces sp. AMCC400023     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6934334..6944993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVT30_RS30560 (CVT30_30830) - 6934670..6935368 (-) 699 WP_045557407.1 SDR family oxidoreductase -
  CVT30_RS30565 (CVT30_30835) - 6935478..6936038 (-) 561 WP_045557406.1 PaaI family thioesterase -
  CVT30_RS30570 (CVT30_30840) - 6936035..6937669 (-) 1635 WP_078853406.1 MFS transporter -
  CVT30_RS30575 (CVT30_30845) - 6937826..6938659 (-) 834 WP_045557405.1 enoyl-CoA hydratase/isomerase family protein -
  CVT30_RS30580 (CVT30_30850) - 6938656..6939276 (-) 621 WP_045557404.1 methyltransferase domain-containing protein -
  CVT30_RS30585 (CVT30_30855) vraR 6939334..6939993 (-) 660 WP_045557403.1 response regulator transcription factor Regulator
  CVT30_RS30590 - 6939972..6940136 (-) 165 WP_159040879.1 hypothetical protein -
  CVT30_RS30595 (CVT30_30860) - 6940263..6941429 (-) 1167 WP_093789195.1 low temperature requirement protein A -
  CVT30_RS30600 (CVT30_30865) - 6941492..6942343 (-) 852 WP_093789196.1 alpha/beta hydrolase -
  CVT30_RS30605 (CVT30_30870) - 6942400..6943215 (-) 816 WP_045557400.1 oxidoreductase -
  CVT30_RS30610 (CVT30_30875) - 6943652..6944662 (-) 1011 WP_196789370.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23505.37 Da        Isoelectric Point: 5.4165

>NTDB_id=215929 CVT30_RS30585 WP_045557403.1 6939334..6939993(-) (vraR) [Streptomyces sp. AMCC400023]
MAEAGVLICDDQELMRVGLRMVVDSQSDLSVVGEAGDGEAAVAKALTLRPDLVLMDVRLPRLDGISATAQVRAALPQTQV
LVITACDRDEYAYAALRAGAGGFLVKDTPAAEMLVAVRGVLRGDTMIAPSVTRRLIDRYVTGAIAPLTDKRLAILTDRER
EVLALVARGLNNTEIAEKLFLGETTVKTHVARILTKLQIRDRIEAVVMAYESGLVRPGG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=215929 CVT30_RS30585 WP_045557403.1 6939334..6939993(-) (vraR) [Streptomyces sp. AMCC400023]
ATGGCGGAGGCCGGTGTGTTGATCTGTGACGACCAGGAGCTGATGCGGGTCGGCCTGCGCATGGTGGTGGACAGCCAGTC
GGACCTCTCGGTCGTCGGCGAAGCCGGGGACGGCGAGGCGGCCGTGGCGAAGGCACTCACGCTGCGCCCGGACCTGGTCC
TCATGGATGTGCGGCTGCCGCGCCTCGACGGCATCTCGGCCACCGCGCAGGTCCGCGCCGCACTGCCGCAGACACAGGTT
CTGGTCATCACCGCCTGCGACCGCGACGAATACGCCTACGCGGCGCTGCGTGCCGGAGCCGGCGGCTTCCTCGTCAAGGA
CACACCGGCTGCGGAGATGCTCGTCGCCGTGCGCGGCGTGCTGCGCGGCGACACGATGATCGCCCCCTCGGTGACCCGAC
GACTGATCGACCGGTATGTCACGGGCGCCATCGCTCCCCTCACCGACAAGCGCCTCGCCATACTGACCGACCGCGAGCGT
GAGGTGCTGGCCCTGGTCGCCCGCGGCCTGAACAACACGGAGATCGCCGAGAAGCTGTTCCTCGGCGAGACCACGGTCAA
GACCCACGTGGCCCGCATCCTCACCAAACTCCAGATCCGCGACCGGATAGAGGCCGTCGTCATGGCCTACGAGAGCGGAC
TGGTTCGCCCTGGCGGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.81

96.347

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

34.956

100

0.361

Multiple sequence alignment