Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CVT30_RS19225 Genome accession   NZ_CP024989
Coordinates   4476957..4477622 (-) Length   221 a.a.
NCBI ID   WP_045558159.1    Uniprot ID   A0ABU4MJ93
Organism   Streptomyces sp. AMCC400023     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4471957..4482622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVT30_RS19205 (CVT30_19445) - 4472565..4473518 (+) 954 WP_093792757.1 ABC transporter ATP-binding protein -
  CVT30_RS19210 (CVT30_19450) - 4473515..4475176 (+) 1662 WP_237313553.1 ABC transporter permease -
  CVT30_RS19215 (CVT30_19455) - 4475432..4475695 (+) 264 WP_234379482.1 hypothetical protein -
  CVT30_RS19220 (CVT30_19460) - 4475678..4476895 (-) 1218 WP_045558158.1 cytochrome P450 -
  CVT30_RS19225 (CVT30_19465) vraR 4476957..4477622 (-) 666 WP_045558159.1 response regulator transcription factor Regulator
  CVT30_RS19230 (CVT30_19470) - 4477619..4478968 (-) 1350 WP_093792769.1 histidine kinase -
  CVT30_RS19235 (CVT30_19475) - 4479089..4479997 (-) 909 WP_045558160.1 alpha/beta hydrolase -
  CVT30_RS19240 (CVT30_19480) kynU 4480262..4481509 (-) 1248 WP_093792763.1 kynureninase -
  CVT30_RS19245 (CVT30_19485) - 4481502..4482347 (-) 846 WP_045558162.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23845.48 Da        Isoelectric Point: 4.6426

>NTDB_id=215909 CVT30_RS19225 WP_045558159.1 4476957..4477622(-) (vraR) [Streptomyces sp. AMCC400023]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGRDAVDRVRELSPDVVLMDIRMPELNGIEATREIVASDGGARVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTKRLITEFSKLAQAPRPSAATQLAYGELTD
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=215909 CVT30_RS19225 WP_045558159.1 4476957..4477622(-) (vraR) [Streptomyces sp. AMCC400023]
ATGACGATCCGCGTGCTGATCGCCGACGACCAGATGATGGTCCGCGAGGGCTTCTCCGTGCTGCTCAACGCGATGCCGGA
CATCGAGGTGGTCGGCGAGGCGGTGAACGGCCGGGACGCCGTCGACCGGGTCCGGGAGCTGTCGCCGGACGTCGTCCTGA
TGGACATCCGGATGCCCGAACTGAACGGCATCGAGGCCACCCGGGAGATCGTCGCGTCGGACGGCGGGGCGAGGGTGCTG
GTGCTGACCACGTTCGACCTGGACGAGTACGTGTACCAGGCGCTGCGCGCGGGCGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTGGCCGACGGGGTAAGGGTGGTGGCCGCCGGTGAGGCCCTGCTCGCGCCGTCCGTCACCAAGCGGC
TGATCACGGAGTTCTCCAAGCTGGCCCAGGCCCCCCGCCCCTCCGCGGCCACCCAGCTGGCGTACGGCGAACTCACCGAC
CGCGAGACCGAGGTCCTGGTCCTGATCGCCCAGGGCCTGTCGAACGCGGAGATCGCGGAGCGCCTGGTGGTCGCCGAGTC
CACGATCAAGACCCATGTGAGCCGGGTCCTGGTCAAACTGGGCCTGCGCGACCGGACGCAGGCGGCGGTGTTCGCGTACG
AGGCGCGGCTGGTCACGCCGGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.661

98.643

0.421
  degU Bacillus subtilis subsp. subtilis str. 168

41.475

98.19

0.407

Multiple sequence alignment