Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SPY_RS08775 Genome accession   NC_002737
Coordinates   1775853..1776620 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes M1 GAS     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770853..1781620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPY_RS08760 (SPy2121) hexB 1771372..1773354 (-) 1983 WP_010922757.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPY_RS08765 (SPy2122) - 1773449..1774600 (-) 1152 WP_014635780.1 tyrosine-type recombinase/integrase -
  SPY_RS09485 - 1774849..1774992 (+) 144 WP_011185066.1 putative holin-like toxin -
  SPY_RS08775 (SPy2125) irvR 1775853..1776620 (-) 768 WP_003058809.1 LexA family transcriptional regulator Regulator
  SPY_RS08780 (SPy2126) - 1776774..1776980 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  SPY_RS08785 (SPy2127) - 1777200..1777781 (+) 582 WP_014635781.1 BRO-N domain-containing protein -
  SPY_RS08790 (SPy2128) - 1777791..1778414 (+) 624 WP_010922760.1 phage repressor protein -
  SPY_RS08795 (SPy2129) - 1778441..1778683 (+) 243 WP_014635782.1 hypothetical protein -
  SPY_RS08800 (SPy2130) - 1778939..1779280 (+) 342 WP_010922762.1 hypothetical protein -
  SPY_RS08805 (SPy2131) - 1779267..1779488 (+) 222 WP_010922763.1 hypothetical protein -
  SPY_RS08810 (SPy2132) - 1779491..1779682 (+) 192 WP_010922764.1 hypothetical protein -
  SPY_RS08815 (SPy2133) - 1779694..1780023 (+) 330 WP_010922765.1 hypothetical protein -
  SPY_RS08820 (SPy2134) - 1780026..1780298 (+) 273 WP_010922766.1 hypothetical protein -
  SPY_RS08825 (SPy2135) - 1780299..1781156 (+) 858 WP_010922767.1 primase alpha helix C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=21590 SPY_RS08775 WP_003058809.1 1775853..1776620(-) (irvR) [Streptococcus pyogenes M1 GAS]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=21590 SPY_RS08775 WP_003058809.1 1775853..1776620(-) (irvR) [Streptococcus pyogenes M1 GAS]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4

Multiple sequence alignment