Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   BWQ98_RS09325 Genome accession   NZ_CP019299
Coordinates   1727123..1727743 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain HKU1-14     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1722123..1732743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWQ98_RS09300 (BWQ98_09310) recA 1722501..1723667 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  BWQ98_RS09305 (BWQ98_09315) cinA 1723722..1724978 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  BWQ98_RS09310 (BWQ98_09320) - 1725062..1726078 (-) 1017 WP_000239282.1 LCP family protein -
  BWQ98_RS09315 (BWQ98_09325) - 1726086..1726604 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  BWQ98_RS09320 (BWQ98_09330) tsaE 1726594..1727037 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  BWQ98_RS09325 (BWQ98_09335) comM 1727123..1727743 (-) 621 WP_000839908.1 hypothetical protein Regulator
  BWQ98_RS09335 (BWQ98_09345) - 1728126..1728584 (-) 459 Protein_1748 transcriptional regulator -
  BWQ98_RS09340 (BWQ98_09350) - 1728777..1730123 (-) 1347 WP_050210214.1 IS1380-like element ISSpn5 family transposase -
  BWQ98_RS09350 (BWQ98_09360) - 1730290..1730697 (-) 408 Protein_1750 helix-turn-helix transcriptional regulator -
  BWQ98_RS09355 (BWQ98_09365) - 1730886..1731056 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=214713 BWQ98_RS09325 WP_000839908.1 1727123..1727743(-) (comM) [Streptococcus pneumoniae strain HKU1-14]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=214713 BWQ98_RS09325 WP_000839908.1 1727123..1727743(-) (comM) [Streptococcus pneumoniae strain HKU1-14]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment