Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SP_RS01840 Genome accession   NC_003028
Coordinates   355159..355848 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 350159..360848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP_RS01815 (SP_0372) gpsB 350268..350597 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SP_RS01825 (SP_0373) - 351083..352240 (+) 1158 WP_000711388.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SP_RS01830 (SP_0374) mapZ 352253..353647 (+) 1395 WP_000039291.1 cell division site-positioning protein MapZ -
  SP_RS01835 (SP_0375) gndA 353723..355147 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  SP_RS01840 (SP_0376) covR 355159..355848 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  SP_RS01845 (SP_0377) cbpC 355947..356969 (+) 1023 WP_000771084.1 choline-binding protein CbpC -
  SP_RS01850 (SP_0378) cbpJ 356987..357985 (+) 999 WP_000698047.1 choline-binding protein CbpJ -
  SP_RS01855 (SP_0379) - 358103..359335 (-) 1233 WP_000765691.1 MFS transporter -
  SP_RS01860 (SP_0380) - 359378..360253 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=21464 SP_RS01840 WP_000518018.1 355159..355848(+) (covR) [Streptococcus pneumoniae TIGR4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=21464 SP_RS01840 WP_000518018.1 355159..355848(+) (covR) [Streptococcus pneumoniae TIGR4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment