Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   SAR_RS08520 Genome accession   NC_002952
Coordinates   1733027..1735228 (-) Length   733 a.a.
NCBI ID   WP_000967506.1    Uniprot ID   A0AAJ4YUY1
Organism   Staphylococcus aureus subsp. aureus MRSA252     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1728027..1740228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAR_RS08505 (SAR1662) lepA 1729531..1731354 (-) 1824 WP_000368338.1 translation elongation factor 4 -
  SAR_RS08510 (SAR1663) rpsT 1731700..1731951 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  SAR_RS08515 (SAR1664) holA 1731996..1732970 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  SAR_RS08520 (SAR1665) comEC 1733027..1735228 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SAR_RS08525 (SAR1666) - 1735233..1735694 (-) 462 WP_000439692.1 ComE operon protein 2 -
  SAR_RS08530 (SAR1667) comEA 1735786..1736472 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  SAR_RS08535 (SAR1668) - 1736512..1737228 (-) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  SAR_RS08540 (SAR1669) rsfS 1737231..1737584 (-) 354 WP_001088020.1 ribosome silencing factor -
  SAR_RS08545 (SAR1670) yqeK 1737585..1738169 (-) 585 WP_001019327.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SAR_RS08550 (SAR1671) nadD 1738159..1738728 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  SAR_RS08555 (SAR1672) yhbY 1738731..1739021 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  SAR_RS08560 (SAR1673) aroE 1739025..1739831 (-) 807 WP_000666750.1 shikimate dehydrogenase -

Sequence

Protein


Download         Length: 733 a.a.        Molecular weight: 84906.94 Da        Isoelectric Point: 10.0190

>NTDB_id=21277 SAR_RS08520 WP_000967506.1 1733027..1735228(-) (comEC) [Staphylococcus aureus subsp. aureus MRSA252]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITNQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGELEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYGNASGL

Nucleotide


Download         Length: 2202 bp        

>NTDB_id=21277 SAR_RS08520 WP_000967506.1 1733027..1735228(-) (comEC) [Staphylococcus aureus subsp. aureus MRSA252]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTTATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTATATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAAATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAAATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTCTTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCCTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAATCAAATTAAAATAAAGGGTATTCAGCTTTTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGTTACTTTTTCCTTTTTTACAG
CAATTGTCGAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCATACTATTCGATTATATTGTTTCCTCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCCGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAGAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAATTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTATAACATTAAACTTATGGATGTAAGGCAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATACTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTTCTA
AAAAAATATAATTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGTAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGAAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGCCAACAAAACGGTCAAGTTACAATAGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(183-441)

Metallo-beta-lactamase superfamily (Lactamase_B)

(474-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Staphylococcus aureus N315

99.045

100

0.99
  comEC Staphylococcus aureus MW2

98.909

100

0.989

Multiple sequence alignment