Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   SAR_RS06260 Genome accession   NC_002952
Coordinates   1277983..1278855 (+) Length   290 a.a.
NCBI ID   WP_000620184.1    Uniprot ID   A0A0E1X7W8
Organism   Staphylococcus aureus subsp. aureus MRSA252     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1272983..1283855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAR_RS06240 (SAR1221) sucC 1273098..1274264 (+) 1167 WP_001020807.1 ADP-forming succinate--CoA ligase subunit beta -
  SAR_RS06245 (SAR1222) sucD 1274286..1275194 (+) 909 WP_000110252.1 succinate--CoA ligase subunit alpha -
  SAR_RS06250 (SAR1223) - 1275421..1276539 (+) 1119 WP_001041658.1 LysM peptidoglycan-binding domain-containing protein -
  SAR_RS06255 (SAR1224) fmhC 1276567..1277811 (+) 1245 WP_000672864.1 FemA/FemB family glycyltransferase FmhC -
  SAR_RS06260 (SAR1225) dprA 1277983..1278855 (+) 873 WP_000620184.1 DNA-processing protein DprA Machinery gene
  SAR_RS06265 (SAR1226) topA 1279029..1281104 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  SAR_RS06270 (SAR1227) trmFO 1281260..1282567 (+) 1308 WP_000195263.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33547.97 Da        Isoelectric Point: 9.5241

>NTDB_id=21266 SAR_RS06260 WP_000620184.1 1277983..1278855(+) (dprA) [Staphylococcus aureus subsp. aureus MRSA252]
MIRLFLLKLYWAHFSTKQIHQFLMAYPNVIKEGGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDTEYPVLLKEIYQFPLLLFYRGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEIGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=21266 SAR_RS06260 WP_000620184.1 1277983..1278855(+) (dprA) [Staphylococcus aureus subsp. aureus MRSA252]
TTGATTAGACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATACCC
TAATGTAATTAAAGAGGGGGGCAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATACTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAGAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGCACATTAGC
ATTAAGAAATAAAATAGAAGAAATAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGTAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X7W8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

98.276

100

0.983
  dprA Staphylococcus aureus N315

97.931

100

0.979

Multiple sequence alignment