Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BVD88_RS12765 Genome accession   NZ_CP018907
Coordinates   2154907..2158056 (-) Length   1049 a.a.
NCBI ID   WP_104916101.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M21273     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2149907..2163056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVD88_RS12715 (BVD88_13285) - 2150397..2150612 (-) 216 Protein_2099 DUF1132 family protein -
  BVD88_RS12720 (BVD88_13290) - 2150731..2151030 (-) 300 WP_002216896.1 hypothetical protein -
  BVD88_RS12725 (BVD88_13295) - 2151058..2151288 (-) 231 WP_002216898.1 hypothetical protein -
  BVD88_RS12730 (BVD88_13300) - 2151515..2151715 (-) 201 WP_002212530.1 hypothetical protein -
  BVD88_RS12735 (BVD88_13305) - 2151719..2152030 (-) 312 WP_025458703.1 hypothetical protein -
  BVD88_RS12740 (BVD88_13310) - 2152042..2153256 (-) 1215 WP_002220093.1 replication initiation factor domain-containing protein -
  BVD88_RS12765 (BVD88_13330) pilC 2154907..2158056 (-) 3150 WP_104916101.1 PilC family type IV pilus tip adhesin Machinery gene
  BVD88_RS12795 (BVD88_13355) - 2159702..2159986 (-) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  BVD88_RS12805 (BVD88_13365) pilA 2160965..2162230 (-) 1266 WP_002224230.1 signal recognition particle-docking protein FtsY Machinery gene

Sequence

Protein


Download         Length: 1049 a.a.        Molecular weight: 115404.28 Da        Isoelectric Point: 9.7146

>NTDB_id=211686 BVD88_RS12765 WP_104916101.1 2154907..2158056(-) (pilC) [Neisseria meningitidis strain M21273]
MNKTWKRQVFRHTALYTAILMFSHTGGGGAQAQENPYAIVMNSQKLPEVKWGNSYKKGELRPEDRDRKFTFTSTYGIKRN
TNITFNNTDYLVSEKNGTAVFGAATYLPPYGKVSGFDTDRLTKRGNAVDWINTTHPGLIGYSYQGITCSSSSCPEFGYKT
QFTFGNSGLAKKTNSSKLDIYEDKSRDNSPIYKLQDYPWLGVSFNLSSDSYVKQKRHNSLVSSFSEDVTQSNGTQSPYKD
RNLVYRTDDYHNKGNYSHQDAHHAIAFYLNAKLHLLDKKQIKNIAQGSELNLGMLKTHIELPKNFNQRSLVGSVVSWTVK
DEGKVSVKLKLPEVKAGRCINKDNPNPKSKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDT
SKPGRYSLKPLSTSEIKSKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPW
TVRASNDDNQFKTINQQLNQQKIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKL
SYIPGTMPRKDIQNTESTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADS
NNPTAVSLFDVKNGNNGNNSNNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLI
KKIDVPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSSDNPSSWTVRTIFSGNKPITSAPAISQLKDKRVVIF
GTGSDLSEDDVDKTDEQYIYGIFDDDTATTGPVNFSGTGGGLLEQVLTEENKTLFLTDYKRSDGSGSKGWVVKLKDGQRV
TVKPTVVLRTAFVTIRKYKDNGCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKQTTKGKSIPIGCMEKDN
GIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMK
RISWREVFY

Nucleotide


Download         Length: 3150 bp        

>NTDB_id=211686 BVD88_RS12765 WP_104916101.1 2154907..2158056(-) (pilC) [Neisseria meningitidis strain M21273]
ATGAATAAAACTTGGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAGGAGAATCCATACGCTATTGTAATGAACAGTCAAAAGCTGCCCGAGGTAAAGTGGGGGAATT
CATATAAAAAAGGGGAGTTGAGGCCCGAAGACAGGGATCGTAAATTTACCTTTACGAGTACTTATGGAATCAAACGCAAC
ACTAATATCACATTCAATAATACCGATTATCTTGTTTCTGAAAAAAACGGTACTGCCGTTTTCGGCGCGGCGACCTACCT
GCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGACCAAGCGCGGCAATGCCGTTGATTGGATTAATACGA
CCCACCCGGGGTTGATAGGCTACAGCTACCAAGGTATCACATGCAGCAGCAGCAGCTGTCCTGAATTTGGCTATAAAACC
CAATTTACCTTCGGTAATTCCGGTTTGGCAAAAAAGACAAACAGCAGCAAGCTGGATATATACGAAGACAAAAGCCGCGA
CAATTCGCCCATTTACAAATTGCAGGATTATCCTTGGTTGGGCGTGTCTTTCAATTTGAGCAGCGATAGCTACGTCAAAC
AAAAGAGACACAATAGTTTGGTATCTTCTTTTAGCGAGGATGTGACGCAGAGCAATGGTACGCAAAGCCCATACAAAGAC
AGAAACCTCGTTTATCGTACAGACGATTACCATAATAAGGGTAATTATAGCCATCAGGACGCACACCACGCCATCGCCTT
TTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAAATCAAAAATATCGCGCAAGGCAGTGAACTTAATTTGGGTA
TGTTGAAAACGCACATCGAGCTGCCGAAAAATTTTAATCAAAGGAGCTTGGTAGGTTCGGTGGTTAGTTGGACGGTTAAA
GATGAGGGAAAAGTCAGCGTCAAACTCAAATTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAAGATAACCCCAATCC
CAAATCCAAAGCCCCTTCCCCCGCCCTGACTGCCCCCGCGCTGTGGTTCGGACCTGTGCAAAATGGCAAGGTGCAGATGT
ATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTTTCCTGCAAAACCTTTCCCGCAAGGATGACACA
AGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATTAAAAGTAAAGAGCCGACTTTCACAGGGCGGCA
AACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGGCAATGAGGTCACTAGTTTTAATGTAAACAACG
GCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGG
ACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAACCAACAACTTAACCAACAAAAAATCCAATACAGCCA
AAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATT
TGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTC
AGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGC
CGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGC
AAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGC
AATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAATGGCAATAATGGCAATAATAGCAATAATAGCAATAATAGCGT
GCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTT
ATGCGACTAAAACCATTGACGACCAACAAAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATT
AAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGA
TATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTGAGCAGCGACAATCCGTCCAGCTGGACTGTAC
GCACTATTTTCAGCGGCAACAAACCGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTC
GGCACGGGCAGCGATTTGAGTGAGGATGATGTTGATAAAACGGACGAACAATATATTTACGGTATCTTTGACGACGATAC
GGCGACGACGGGTCCTGTAAACTTCAGCGGTACGGGAGGCGGGCTGCTCGAGCAAGTGCTTACTGAGGAAAATAAAACCT
TATTCCTGACCGATTACAAGCGATCCGACGGCTCGGGCAGCAAAGGGTGGGTAGTGAAATTGAAGGACGGACAGCGCGTT
ACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAAAGACAACGGCTGCGGCGCGGAAAC
CGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCCGACAATA
CGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACAAT
GGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATT
TTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGAACATTCAAAGAAGGTAAAAAACCCGCCCGCAATAACCGGTGCT
TCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAA
CGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(519-857)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.904

100

0.718

Multiple sequence alignment