Detailed information NTG0211687

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: BVD88_RS12805
• Genome accession: NZ_CP018907
• Coordinates: 2160965..2162230 (-)
• Length: 421 a.a.
• NCBI ID: WP_002224230.1
• Uniprot ID: A1KR71
• Organism: Neisseria meningitidis strain M21273
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2155965..2167230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BVD88_RS12795 (BVD88_13355)	-	2159702..2159986 (-)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
BVD88_RS12805 (BVD88_13365)	pilA	2160965..2162230 (-)	1266	WP_002224230.1	signal recognition particle-docking protein FtsY	Machinery gene
BVD88_RS12815 (BVD88_13375)	msrAB	2162375..2163943 (+)	1569	WP_002224229.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
BVD88_RS12820 (BVD88_13380)	-	2164045..2164530 (-)	486	WP_002215245.1	CinA family protein	-
BVD88_RS12825 (BVD88_13385)	-	2164556..2165404 (-)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
BVD88_RS12830 (BVD88_13390)	-	2165498..2166499 (-)	1002	WP_002223261.1	thiamine ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45333.62 Da
• Isoelectric Point: 4.5064

>NTDB_id=211687 BVD88_RS12805 WP_002224230.1 2160965..2162230(-) (pilA) [Neisseria meningitidis strain M21273]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEEVESLTESVKEQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=211687 BVD88_RS12805 WP_002224230.1 2160965..2162230(-) (pilA) [Neisseria meningitidis strain M21273]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGAGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAGGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAAAAACCATTGG
TCTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGACACTTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAGGCATGGGGCGAACGCAACAACGTTACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: A1KR71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.349	100	0.933