Detailed information NTG0211651

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: BVD88_RS01800
• Genome accession: NZ_CP018907
• Coordinates: 294103..294963 (-)
• Length: 286 a.a.
• NCBI ID: WP_002241067.1
• Uniprot ID: A1KVV2
• Organism: Neisseria meningitidis strain M21273
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 289103..299963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BVD88_RS01750 (BVD88_01865)	rplU	289109..289417 (-)	309	WP_002216394.1	50S ribosomal protein L21	-
BVD88_RS01760 (BVD88_01875)	ispB	289641..290615 (+)	975	WP_096111589.1	octaprenyl diphosphate synthase	-
BVD88_RS01765 (BVD88_01880)	-	290620..291066 (+)	447	WP_104916064.1	DUF441 domain-containing protein	-
BVD88_RS01785 (BVD88_01890)	pilF	291506..293182 (+)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
BVD88_RS01790 (BVD88_01895)	-	293267..293476 (-)	210	WP_096109148.1	DNA gyrase inhibitor YacG	-
BVD88_RS01795 (BVD88_01900)	coaE	293469..294101 (-)	633	WP_002224873.1	dephospho-CoA kinase	-
BVD88_RS01800 (BVD88_01905)	pilD	294103..294963 (-)	861	WP_002241067.1	prepilin peptidase	Machinery gene
BVD88_RS01805 (BVD88_01910)	pilG	295037..296262 (-)	1226	Protein_291	type 4 pilus assembly protein PilG	-
BVD88_RS01815 (BVD88_01915)	pgi	296772..298415 (+)	1644	WP_104916065.1	glucose-6-phosphate isomerase	-
BVD88_RS01820 (BVD88_01920)	-	298385..298615 (+)	231	WP_025458514.1	hypothetical protein	-
BVD88_RS01825 (BVD88_01925)	dapD	298625..299446 (+)	822	WP_002220281.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31331.48 Da
• Isoelectric Point: 9.1920

>NTDB_id=211651 BVD88_RS01800 WP_002241067.1 294103..294963(-) (pilD) [Neisseria meningitidis strain M21273]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKKHLNLPLTEKESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=211651 BVD88_RS01800 WP_002241067.1 294103..294963(-) (pilD) [Neisseria meningitidis strain M21273]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAAAACATTTAAACCTGCCGCTGA
CCGAAAAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTATTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A1KVV2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	96.14	99.65	0.958
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434
pilD	Vibrio campbellii strain DS40M4	44.565	96.503	0.43