Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LPG_RS13355 Genome accession   NC_002942
Coordinates   2993753..2994412 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila str. Philadelphia     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2988753..2999412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPG_RS13340 (lpg2643) - 2989553..2990212 (+) 660 WP_010948343.1 hypothetical protein -
  LPG_RS13345 (lpg2644) - 2990380..2991861 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  LPG_RS13350 (lpg2645) uvrC 2991885..2993741 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  LPG_RS13355 (lpg2646) letA 2993753..2994412 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  LPG_RS13360 (lpg2647) phhA 2994537..2995355 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  LPG_RS13365 (lpg2648) - 2995794..2996891 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  LPG_RS13370 (lpg2649) cgtA 2996850..2997875 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  LPG_RS13375 (lpg2650) rpmA 2998090..2998368 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  LPG_RS13380 (lpg2651) rplU 2998381..2998692 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=21116 LPG_RS13355 WP_011216518.1 2993753..2994412(-) (letA) [Legionella pneumophila subsp. pneumophila str. Philadelphia]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=21116 LPG_RS13355 WP_011216518.1 2993753..2994412(-) (letA) [Legionella pneumophila subsp. pneumophila str. Philadelphia]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment