Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CR535_RS10710 Genome accession   NZ_CP024131
Coordinates   2021950..2022606 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 14EC007     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016950..2027606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR535_RS10680 (CR535_10605) dcyD 2017829..2018815 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  CR535_RS10685 (CR535_10610) tcyL 2018830..2019498 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CR535_RS10690 (CR535_10615) tcyN 2019495..2020247 (+) 753 WP_033803532.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CR535_RS10695 (CR535_10620) sdiA 2020477..2021199 (+) 723 WP_001154287.1 transcriptional regulator SdiA -
  CR535_RS10700 (CR535_10625) yecF 2021267..2021491 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CR535_RS28690 yecU 2021478..2021654 (-) 177 WP_000590347.1 protein YecU -
  CR535_RS29660 (CR535_10630) - 2021692..2021808 (-) 117 WP_001302039.1 hypothetical protein -
  CR535_RS10710 (CR535_10635) letA 2021950..2022606 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CR535_RS10715 (CR535_10640) uvrC 2022603..2024435 (+) 1833 WP_053887286.1 excinuclease ABC subunit UvrC Machinery gene
  CR535_RS10720 (CR535_10645) pgsA 2024492..2025040 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CR535_RS10740 (CR535_10665) yecA 2025690..2026355 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=210818 CR535_RS10710 WP_000611335.1 2021950..2022606(+) (letA) [Escherichia coli strain 14EC007]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=210818 CR535_RS10710 WP_000611335.1 2021950..2022606(+) (letA) [Escherichia coli strain 14EC007]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAGCCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486