Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilF   Type   Machinery gene
Locus tag   HD_RS01300 Genome accession   NC_002940
Coordinates   252640..253185 (-) Length   181 a.a.
NCBI ID   WP_010944348.1    Uniprot ID   Q7VNZ5
Organism   [Haemophilus] ducreyi 35000HP     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 247640..258185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HD_RS01285 (HD0315) dppD 248208..249212 (+) 1005 WP_010944345.1 dipeptide ABC transporter ATP-binding protein -
  HD_RS01290 (HD0316) - 249205..250194 (+) 990 WP_041603353.1 peptide ABC transporter ATP-binding protein -
  HD_RS01295 (HD0317) - 250251..252569 (-) 2319 WP_010944347.1 Tex family protein -
  HD_RS01300 (HD0318) pilF 252640..253185 (-) 546 WP_010944348.1 type IV pilus biogenesis/stability protein PilW Machinery gene
  HD_RS01305 (HD0319) - 253224..254405 (-) 1182 WP_010944349.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
  HD_RS01325 (HD0320) gltX 255170..256609 (+) 1440 WP_010944350.1 glutamate--tRNA ligase -
  HD_RS01335 (HD0321) sodA 256863..257504 (-) 642 WP_010944351.1 superoxide dismutase [Mn] -
  HD_RS01340 (HD0322) - 257643..257996 (-) 354 WP_010944352.1 RidA family protein -

Sequence

Protein


Download         Length: 181 a.a.        Molecular weight: 20237.97 Da        Isoelectric Point: 8.1148

>NTDB_id=21065 HD_RS01300 WP_010944348.1 252640..253185(-) (pilF) [[Haemophilus] ducreyi 35000HP]
MAKILKNLTACFAIVMLLGCSSSYTGSSVSTFNRNKIVQARINLALAYLEQHHFAKAKENIDKALQHDAQDYLPYSALAY
YYQQIGDLTQAANAYQTALTLGNNTPDVLNNYGTFLCHQGKFDLAYQQFEQAIKSQQSYYHQADSLENIILCAKQEKNTA
KIAIALQQLTALDKTRADALR

Nucleotide


Download         Length: 546 bp        

>NTDB_id=21065 HD_RS01300 WP_010944348.1 252640..253185(-) (pilF) [[Haemophilus] ducreyi 35000HP]
ATGGCAAAAATTTTAAAAAATCTAACCGCTTGTTTCGCTATTGTTATGCTGTTAGGTTGTTCCTCTTCTTATACTGGCTC
ATCAGTATCCACATTTAACCGAAATAAAATAGTCCAAGCACGCATTAATTTAGCATTAGCTTATCTAGAACAACACCATT
TTGCTAAAGCAAAAGAAAATATTGATAAAGCACTCCAACATGACGCTCAAGATTATTTACCTTATTCAGCACTGGCTTAC
TATTATCAACAAATAGGTGATTTAACTCAAGCCGCTAACGCCTACCAGACAGCACTAACTCTAGGAAATAATACGCCTGA
TGTATTAAATAATTACGGTACTTTTTTATGCCATCAAGGTAAATTTGACCTCGCTTATCAGCAATTTGAACAAGCGATAA
AGAGTCAACAATCTTACTATCATCAAGCAGATAGCTTAGAGAATATTATTCTTTGTGCCAAACAAGAGAAAAATACCGCT
AAAATAGCTATTGCATTACAACAATTAACAGCGCTAGACAAAACACGCGCAGATGCACTACGGTAA

Domains

Predicted by InterproScan.

Tetratricopeptide repeat (TPR_16)

(77-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7VNZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilF Glaesserella parasuis strain SC1401

58.289

100

0.602
  pilF/pilF2 Haemophilus influenzae Rd KW20

43.889

99.448

0.436

Multiple sequence alignment