Detailed information NTG0210127

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BTZ13_RS05290
• Genome accession: NZ_CP018776
• Coordinates: 1160661..1161704 (+)
• Length: 347 a.a.
• NCBI ID: WP_047132847.1
• Uniprot ID: A0A143P7E7
• Organism: Staphylococcus condimenti strain StO 2014-01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1155661..1166704

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BTZ13_RS05265 (BTZ13_05265)	-	1156642..1157367 (+)	726	WP_047132842.1	type 1 glutamine amidotransferase	-
BTZ13_RS05270 (BTZ13_05270)	-	1157417..1158403 (-)	987	WP_047132843.1	FUSC family protein	-
BTZ13_RS05275 (BTZ13_05275)	map	1158651..1159418 (+)	768	WP_047132844.1	type I methionyl aminopeptidase	-
BTZ13_RS05280 (BTZ13_05280)	-	1159552..1159947 (+)	396	WP_047132845.1	hypothetical protein	-
BTZ13_RS05285 (BTZ13_05285)	liaF	1159963..1160664 (+)	702	WP_047132846.1	cell wall-active antibiotics response protein LiaF	-
BTZ13_RS05290 (BTZ13_05290)	vraS	1160661..1161704 (+)	1044	WP_047132847.1	sensor histidine kinase	Regulator
BTZ13_RS05295 (BTZ13_05295)	vraR	1161694..1162323 (+)	630	WP_047132848.1	response regulator transcription factor	Regulator
BTZ13_RS05300 (BTZ13_05300)	-	1162372..1162950 (-)	579	WP_047132849.1	beta-class carbonic anhydrase	-
BTZ13_RS05305 (BTZ13_05305)	-	1163152..1164228 (-)	1077	WP_047132850.1	YihY/virulence factor BrkB family protein	-
BTZ13_RS05310 (BTZ13_05310)	-	1164348..1164644 (-)	297	WP_047132851.1	hypothetical protein	-
BTZ13_RS05315 (BTZ13_05315)	-	1164652..1165116 (-)	465	WP_047132852.1	low molecular weight protein-tyrosine-phosphatase	-
BTZ13_RS05320 (BTZ13_05320)	-	1165352..1165558 (+)	207	WP_047132853.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.54 Da
• Isoelectric Point: 5.0629

>NTDB_id=210127 BTZ13_RS05290 WP_047132847.1 1160661..1161704(+) (vraS) [Staphylococcus condimenti strain StO 2014-01]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIVFFQGMFYTQIFGIPVFLFLNIIVILMCIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQNIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=210127 BTZ13_RS05290 WP_047132847.1 1160661..1161704(+) (vraS) [Staphylococcus condimenti strain StO 2014-01]
ATGAACCATTATATAAGAGCGATAGGTTCAATGTTAATATTGATTTACAGCATTTTAGCTATTTTCTTTTTCATCGATAA
AGTCTTTGTAAATATTGTCTTTTTTCAAGGAATGTTCTATACACAAATTTTCGGAATTCCAGTTTTTTTGTTTTTAAATA
TCATTGTAATATTGATGTGTATTATCGTAGGTTCTGTATTAGCGTATAAAGTGAACCAGCAAAATCATTGGATTAAAGAC
CAAATTGAACATTCTATTGAAGGTGAAGTCGTAGGTATTAATGATCAAAATATCGAACTTTATCAAGAGACGTTAGATAT
CTATCATATGTTGGTACCTTTAAATCAAGAATTGCACCGCTTACGTATTAAAACACAAGATTTAACGAATGAAACTTATA
ATTTAAATGATACAAAAGTAAAAAAAATTATAGAAGATGAACGTCAACGTTTAGCAAGAGAACTACATGACTCGGTGAGC
CAGCAATTATTTGCTGCAAGTATGATGTTGTCTGCTATAAAGGAAACTAAGTTAGAACCGCCTTTAGATCAACAAATTCC
AACACTTGAAAAGATGGTACAAGATTCACAACTTGAAATGCGTGCTTTATTGCTTCATTTACGTCCATTAGGCTTAAAGG
ACCGTTCATTAGGTGAAGGTATTAAAGACTTGGTTGTAGACTTGCAGAAAAAAGTTCCGATGAAGGTAGTTTATGATATC
GAAGATTTTGAAGTGCCAAAAGGGATAGAAGATCATTTATTCCGAATAACACAAGAAGGTATATCAAACACTTTGCGACA
TGCCGAAGGTACTAAATTGACGATAGATTTATATAATAAAGACGATTATTTACTATTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A143P7E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	85.591	100	0.856