Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | BSG37_RS00395 | Genome accession | NZ_CP018768 |
| Coordinates | 77504..78853 (-) | Length | 449 a.a. |
| NCBI ID | WP_000815646.1 | Uniprot ID | Q9XB96 |
| Organism | Staphylococcus aureus strain UCI 28 isolate ST5 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 39245..78853 | 77504..78853 | within | 0 |
Gene organization within MGE regions
Location: 39245..78853
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BSG37_RS00195 (BSG37_00195) | ccrB | 39245..40873 (-) | 1629 | WP_001631035.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BSG37_RS00200 (BSG37_00200) | ccrA | 40870..42231 (-) | 1362 | WP_001631036.1 | cassette chromosome recombinase CcrA | Machinery gene |
| BSG37_RS00205 (BSG37_00205) | - | 42418..43047 (-) | 630 | Protein_35 | hypothetical protein | - |
| BSG37_RS00210 (BSG37_00210) | - | 43056..43394 (+) | 339 | Protein_36 | recombinase family protein | - |
| BSG37_RS00215 (BSG37_00215) | - | 43506..43865 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| BSG37_RS00220 (BSG37_00220) | - | 44072..44398 (+) | 327 | WP_000391495.1 | ArsR/SmtB family transcription factor | - |
| BSG37_RS00225 (BSG37_00225) | - | 44728..46653 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| BSG37_RS00230 (BSG37_00230) | - | 47981..49237 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| BSG37_RS00235 (BSG37_00235) | - | 49652..49891 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| BSG37_RS00240 (BSG37_00240) | - | 49923..50597 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| BSG37_RS00245 (BSG37_00245) | - | 50688..51671 (-) | 984 | Protein_43 | protein rep | - |
| BSG37_RS00250 (BSG37_00250) | mobV | 51916..53178 (-) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| BSG37_RS00255 (BSG37_00255) | bleO | 53685..54089 (-) | 405 | WP_031879245.1 | bleomycin binding protein | - |
| BSG37_RS00260 (BSG37_00260) | aadD1 | 54306..55067 (-) | 762 | WP_001014230.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| BSG37_RS00265 (BSG37_00265) | - | 55269..55943 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| BSG37_RS00270 (BSG37_00270) | - | 56208..56951 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| BSG37_RS00275 (BSG37_00275) | - | 57048..57476 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| BSG37_RS00280 (BSG37_00280) | mecA | 57522..59531 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| BSG37_RS00285 (BSG37_00285) | mecR1 | 59628..61385 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| BSG37_RS00290 (BSG37_00290) | mecI | 61385..61756 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| BSG37_RS15020 | psm-mec | 61841..61909 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| BSG37_RS00305 (BSG37_00305) | - | 62243..63373 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| BSG37_RS00310 (BSG37_00310) | cstB | 63487..64821 (-) | 1335 | Protein_55 | persulfide dioxygenase-sulfurtransferase CstB | - |
| BSG37_RS00315 (BSG37_00315) | - | 64854..65918 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| BSG37_RS00320 (BSG37_00320) | cstR | 66053..66313 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| BSG37_RS00325 (BSG37_00325) | - | 66313..66951 (+) | 639 | Protein_58 | sulfite exporter TauE/SafE family protein | - |
| BSG37_RS00335 (BSG37_00335) | - | 67296..67958 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| BSG37_RS15510 | - | 68350..68409 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| BSG37_RS00345 (BSG37_00345) | erm(A) | 68459..69190 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| BSG37_RS00350 (BSG37_00350) | - | 69316..70098 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| BSG37_RS00355 (BSG37_00355) | - | 70249..70626 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| BSG37_RS00360 (BSG37_00360) | - | 70633..72525 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| BSG37_RS00365 (BSG37_00365) | - | 72522..73607 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| BSG37_RS00370 (BSG37_00370) | - | 73726..74043 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| BSG37_RS00375 (BSG37_00375) | - | 74064..74570 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| BSG37_RS00380 (BSG37_00380) | - | 74588..74899 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| BSG37_RS00385 (BSG37_00385) | - | 74986..75336 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BSG37_RS00390 (BSG37_00390) | ccrB | 75854..77482 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BSG37_RS00395 (BSG37_00395) | ccrA | 77504..78853 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52607.20 Da Isoelectric Point: 9.9585
>NTDB_id=210078 BSG37_RS00395 WP_000815646.1 77504..78853(-) (ccrA) [Staphylococcus aureus strain UCI 28 isolate ST5]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=210078 BSG37_RS00395 WP_000815646.1 77504..78853(-) (ccrA) [Staphylococcus aureus strain UCI 28 isolate ST5]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
100 |
100 |
1 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |