Detailed information NTG0020972

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAV_RS14340
• Genome accession: NC_002758
• Coordinates: 2776738..2777625 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus Mu50
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2771738..2782625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAV_RS14305	-	2771757..2771849 (+)	93	WP_010956583.1	hypothetical protein	-
SAV_RS14310 (SAV2621)	-	2771957..2772454 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAV_RS14315	-	2772464..2772724 (-)	261	WP_001791974.1	hypothetical protein	-
SAV_RS14320	-	2773106..2773219 (-)	114	Protein_2706	hypothetical protein	-
SAV_RS14330 (SAV2622)	-	2773878..2775878 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAV_RS14335 (SAV2623)	-	2775875..2776630 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAV_RS14340 (SAV2624)	braS	2776738..2777625 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAV_RS14345 (SAV2625)	braR	2777636..2778301 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAV_RS14350 (SAV2626)	-	2778327..2778527 (-)	201	WP_000604730.1	hypothetical protein	-
SAV_RS14360 (SAV2627)	-	2778725..2780149 (+)	1425	WP_000953755.1	alkaline phosphatase	-
SAV_RS16080	-	2780209..2780310 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAV_RS14365 (SAV2628)	-	2780432..2780887 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAV_RS14370 (SAV2629)	-	2781132..2781893 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=20972 SAV_RS14340 WP_000143425.1 2776738..2777625(-) (braS) [Staphylococcus aureus subsp. aureus Mu50]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=20972 SAV_RS14340 WP_000143425.1 2776738..2777625(-) (braS) [Staphylococcus aureus subsp. aureus Mu50]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1