Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CRM97_RS08575 Genome accession   NZ_CP023866
Coordinates   1615001..1615666 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain FDAARGOS_421     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610001..1620666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRM97_RS08560 (CRM97_08560) groES 1611857..1612117 (+) 261 WP_002825273.1 co-chaperone GroES -
  CRM97_RS08565 (CRM97_08565) groL 1612138..1613775 (+) 1638 WP_002860445.1 chaperonin GroEL -
  CRM97_RS08570 (CRM97_08570) dccS 1613818..1615008 (-) 1191 WP_002855957.1 two-component system sensor histidine kinase DccS -
  CRM97_RS08575 (CRM97_08575) ciaR 1615001..1615666 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  CRM97_RS08580 (CRM97_08580) - 1615814..1616413 (+) 600 WP_002855731.1 bacteriohemerythrin -
  CRM97_RS08585 (CRM97_08585) - 1616424..1616672 (+) 249 WP_002853192.1 ribbon-helix-helix domain-containing protein -
  CRM97_RS08595 (CRM97_08595) - 1616930..1618177 (-) 1248 WP_002853241.1 ArsS family sensor histidine kinase -
  CRM97_RS08600 (CRM97_08600) - 1618174..1618848 (-) 675 WP_002853196.1 response regulator transcription factor -
  CRM97_RS08605 (CRM97_08605) htrA 1618924..1620342 (-) 1419 WP_002860448.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=209330 CRM97_RS08575 WP_002853205.1 1615001..1615666(-) (ciaR) [Campylobacter jejuni strain FDAARGOS_421]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=209330 CRM97_RS08575 WP_002853205.1 1615001..1615666(-) (ciaR) [Campylobacter jejuni strain FDAARGOS_421]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGAGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTGCTTAAAAATAAAAACAACTTTTTAAGTACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362

Multiple sequence alignment