Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CR208_RS13665 Genome accession   NZ_CP023541
Coordinates   2812546..2813202 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2807546..2818202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR208_RS13635 (AWA97_14435) yecA 2808797..2809462 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  CR208_RS13655 (AWA97_14455) pgsA 2810112..2810660 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CR208_RS13660 (AWA97_14460) uvrC 2810717..2812549 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  CR208_RS13665 (AWA97_14465) letA 2812546..2813202 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CR208_RS25620 - 2813344..2813415 (+) 72 Protein_2662 transcriptional regulator -
  CR208_RS13670 yecU 2813498..2813674 (+) 177 WP_000590347.1 protein YecU -
  CR208_RS13675 (AWA97_14470) yecF 2813661..2813885 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  CR208_RS13680 (AWA97_14475) sdiA 2813952..2814674 (-) 723 WP_021293341.1 transcriptional regulator SdiA -
  CR208_RS13685 (AWA97_14480) tcyN 2814904..2815656 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CR208_RS13690 (AWA97_14485) tcyL 2815653..2816321 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  CR208_RS13695 (AWA97_14490) dcyD 2816336..2817322 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=208097 CR208_RS13665 WP_000611335.1 2812546..2813202(-) (letA) [Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=208097 CR208_RS13665 WP_000611335.1 2812546..2813202(-) (letA) [Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment