Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BOQ57_RS20305 Genome accession   NZ_CP018201
Coordinates   4333590..4334831 (+) Length   413 a.a.
NCBI ID   WP_011707570.1    Uniprot ID   A0KPV8
Organism   Aeromonas hydrophila strain MX16A     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4328590..4339831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BOQ57_RS20275 (BOQ57_20170) ampD 4328945..4329517 (-) 573 WP_073351944.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  BOQ57_RS20280 (BOQ57_20175) - 4329665..4330135 (+) 471 WP_024944772.1 retropepsin-like aspartic protease -
  BOQ57_RS20285 (BOQ57_20180) nadC 4330141..4330998 (+) 858 WP_073351948.1 carboxylating nicotinate-nucleotide diphosphorylase -
  BOQ57_RS20295 (BOQ57_20190) tapA 4331321..4331764 (+) 444 WP_073352603.1 type IVa pilus major pilin TapA -
  BOQ57_RS20300 (BOQ57_20195) pilB 4331768..4333474 (+) 1707 WP_073351950.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  BOQ57_RS20305 (BOQ57_20200) pilC 4333590..4334831 (+) 1242 WP_011707570.1 type II secretion system F family protein Machinery gene
  BOQ57_RS20310 (BOQ57_20205) pilD 4334854..4335726 (+) 873 WP_065475375.1 A24 family peptidase Machinery gene
  BOQ57_RS20315 (BOQ57_20210) coaE 4335745..4336359 (+) 615 WP_073351951.1 dephospho-CoA kinase -
  BOQ57_RS20320 (BOQ57_20215) zapD 4336397..4337119 (+) 723 WP_043160635.1 cell division protein ZapD -
  BOQ57_RS20325 (BOQ57_20220) yacG 4337129..4337323 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  BOQ57_RS20330 (BOQ57_20225) mutT 4337384..4337797 (-) 414 WP_174892455.1 8-oxo-dGTP diphosphatase MutT -
  BOQ57_RS20335 (BOQ57_20230) - 4337806..4338990 (-) 1185 WP_073351955.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45422.58 Da        Isoelectric Point: 9.8637

>NTDB_id=207191 BOQ57_RS20305 WP_011707570.1 4333590..4334831(+) (pilC) [Aeromonas hydrophila strain MX16A]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=207191 BOQ57_RS20305 WP_011707570.1 4333590..4334831(+) (pilC) [Aeromonas hydrophila strain MX16A]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGTGGGGTGAACCGCAAGGGCCA
GAAAGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGTTATTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCTCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCAGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAGACCGGCACCCCTATGTCCGAGGCGCTGCGCCGCCATCCCC
GTCATTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCTCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTTGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCATCTTCACCCAATTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATTTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCGGTGGTTGGCATGATATTGCACAAGGCCGCTATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCACTAGTGGATGCCTTGGTCTCTGCGGCAGGTGCCTCCGGTAACTATGTCTACCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCAGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0KPV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment