Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   BSR20_RS01580 Genome accession   NZ_CP018189
Coordinates   288275..289804 (+) Length   509 a.a.
NCBI ID   WP_014633596.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 283275..294804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR20_RS10560 - 283529..283651 (+) 123 Protein_248 energy-coupling factor transporter transmembrane protein EcfT -
  BSR20_RS01555 (BSR20_01545) - 283741..284412 (-) 672 WP_002886585.1 potassium channel family protein -
  BSR20_RS01560 (BSR20_01550) - 284452..285816 (-) 1365 WP_002886586.1 TrkH family potassium uptake protein -
  BSR20_RS01565 (BSR20_01555) rsmG 285885..286598 (-) 714 WP_002886587.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BSR20_RS01570 (BSR20_01560) - 286897..287433 (+) 537 WP_045768772.1 DUF177 domain-containing protein -
  BSR20_RS01575 (BSR20_01565) covR 287589..288278 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  BSR20_RS01580 (BSR20_01570) covS 288275..289804 (+) 1530 WP_014633596.1 HAMP domain-containing histidine kinase Regulator
  BSR20_RS01585 (BSR20_01575) nrdR 289926..290405 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  BSR20_RS01590 (BSR20_01580) - 290402..291577 (+) 1176 WP_045771723.1 DnaD domain protein -
  BSR20_RS01595 (BSR20_01585) dnaI 291581..292483 (+) 903 WP_013990064.1 primosomal protein DnaI -
  BSR20_RS01600 (BSR20_01590) der 292588..293898 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  BSR20_RS01605 (BSR20_01595) - 293963..294592 (+) 630 WP_013990065.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58037.45 Da        Isoelectric Point: 5.3910

>NTDB_id=206899 BSR20_RS01580 WP_014633596.1 288275..289804(+) (covS) [Streptococcus salivarius strain ICDC3]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALENEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=206899 BSR20_RS01580 WP_014633596.1 288275..289804(+) (covS) [Streptococcus salivarius strain ICDC3]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCTATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAAATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCGCGTAACC
GTACGACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTCTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986

Multiple sequence alignment