Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   BSR19_RS01890 Genome accession   NZ_CP018187
Coordinates   357801..359120 (+) Length   439 a.a.
NCBI ID   WP_156246369.1    Uniprot ID   A0AB37D8J5
Organism   Streptococcus salivarius strain ICDC2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 352801..364120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS01865 (BSR19_01865) - 353676..354440 (+) 765 WP_002883723.1 ABC transporter ATP-binding protein -
  BSR19_RS01870 (BSR19_01870) - 354440..355150 (+) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  BSR19_RS01875 (BSR19_01875) - 355285..355944 (+) 660 WP_037600377.1 CBS and ACT domain-containing protein -
  BSR19_RS01880 (BSR19_01880) cysK 356092..357018 (-) 927 WP_002883742.1 cysteine synthase A -
  BSR19_RS01885 (BSR19_01885) - 357120..357746 (-) 627 WP_060973192.1 YigZ family protein -
  BSR19_RS01890 (BSR19_01890) comFA/cflA 357801..359120 (+) 1320 WP_156246369.1 DEAD/DEAH box helicase Machinery gene
  BSR19_RS01895 (BSR19_01895) - 359101..359763 (+) 663 WP_156246370.1 ComF family protein -
  BSR19_RS01900 (BSR19_01900) hpf 359842..360390 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50647.83 Da        Isoelectric Point: 9.7608

>NTDB_id=206835 BSR19_RS01890 WP_156246369.1 357801..359120(+) (comFA/cflA) [Streptococcus salivarius strain ICDC2]
MVPKEYYGRLFTKEQLPVDYHPEALTLESMIKVDKQLRCKRCYSRIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWFGELTPYQAKVSEKLLRTYQKQKDSLVHAVTGAGKTEMIYNIVAYVLENKGHVAIASPRVDVCRELFLR
MKRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQSFDLVIVDEVDAYPFVGNVMLNHAVEQAKTQTGRFIYLTATST
LSLEEQVRLGTLEKHHLARRFHGNPLVLPKFFWQGRLQKSLTRGKLSRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEKRSTIVEKFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKAMNKKGGFNNEVSAM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=206835 BSR19_RS01890 WP_156246369.1 357801..359120(+) (comFA/cflA) [Streptococcus salivarius strain ICDC2]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAGCAGTTGCCAGTGGACTATCACCCAGAGGCTTTAACATT
AGAAAGTATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCGGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGTAGAGCATGTATTGTCTTTGGTAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCCAAA
ACATCAGAAATTGAATTTCCTGTTTTGAAGTGGTTTGGAGAACTGACTCCCTATCAAGCTAAGGTCTCAGAGAAACTTTT
GAGAACTTATCAAAAACAGAAAGATAGTCTCGTACATGCTGTGACCGGTGCTGGTAAGACAGAAATGATTTATAACATCG
TTGCCTATGTTCTTGAAAATAAAGGTCATGTAGCTATCGCAAGTCCTAGGGTTGATGTTTGTCGAGAATTATTTCTACGT
ATGAAAAGGGATTTTACTTGTAGTATTTCCCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACACATCAACTACTAAAGTTTTACCAGAGTTTTGACTTAGTTATTGTAGATGAAGTAGACGCATATCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTAGAACAGGCGAAGACCCAAACCGGTCGATTTATTTACTTAACAGCGACTTCAACA
TTATCTTTAGAAGAGCAAGTTCGACTTGGGACTTTAGAAAAACATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTTCTGGCAGGGCAGATTACAAAAATCTCTGACAAGAGGCAAGCTTTCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAATTTCCTCTATTAATCTTCTTTCCAAATATAGCGATAGGTGAAAAGTTTACAAGTATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGCGAGAAGCGTTCAACTATCGTAGAGAAGTT
CCGAGAAAAAGAACTGTCTATCTTAGTGACAACAACTATCCTCGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATTGGAGGTCGAGTTGGAAGATCACCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGGTGTCGAGAAGAGATAAAAGCTATGAA
TAAAAAAGGAGGGTTTAACAATGAAGTGTCTGCTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(292-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae Rx1

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae D39

55.916

98.178

0.549
  comFA/cflA Streptococcus pneumoniae R6

55.916

98.178

0.549
  comFA/cflA Streptococcus mitis NCTC 12261

55.069

98.861

0.544
  comFA/cflA Streptococcus mitis SK321

54.524

98.178

0.535
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

37.011

99.089

0.367

Multiple sequence alignment