Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   BSR19_RS01655 Genome accession   NZ_CP018187
Coordinates   307613..309142 (+) Length   509 a.a.
NCBI ID   WP_060973171.1    Uniprot ID   A0AB37D8D3
Organism   Streptococcus salivarius strain ICDC2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 302613..314142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS01630 (BSR19_01630) - 303078..303749 (-) 672 WP_002883759.1 potassium channel family protein -
  BSR19_RS01635 (BSR19_01635) - 303789..305153 (-) 1365 WP_081260152.1 TrkH family potassium uptake protein -
  BSR19_RS01640 (BSR19_01640) rsmG 305222..305935 (-) 714 WP_048673867.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BSR19_RS01645 (BSR19_01645) - 306235..306771 (+) 537 WP_037600313.1 DUF177 domain-containing protein -
  BSR19_RS01650 (BSR19_01650) covR 306927..307616 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  BSR19_RS01655 (BSR19_01655) covS 307613..309142 (+) 1530 WP_060973171.1 HAMP domain-containing histidine kinase Regulator
  BSR19_RS01660 (BSR19_01660) nrdR 309264..309743 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  BSR19_RS01665 (BSR19_01665) - 309740..310915 (+) 1176 WP_060973172.1 DnaD domain protein -
  BSR19_RS01670 (BSR19_01670) dnaI 310919..311821 (+) 903 WP_002883792.1 primosomal protein DnaI -
  BSR19_RS01675 (BSR19_01675) der 311927..313237 (+) 1311 WP_037597430.1 ribosome biogenesis GTPase Der -
  BSR19_RS01680 (BSR19_01680) - 313301..313930 (+) 630 WP_060973173.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58036.32 Da        Isoelectric Point: 4.9641

>NTDB_id=206833 BSR19_RS01655 WP_060973171.1 307613..309142(+) (covS) [Streptococcus salivarius strain ICDC2]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISDEDIEHIFERFYRSDKARNRTSTQSGVGIGLSILYQIVEAYRCRIE
VSSELGVGTCFDFYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=206833 BSR19_RS01655 WP_060973171.1 307613..309142(+) (covS) [Streptococcus salivarius strain ICDC2]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAACACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATTTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGCCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCGGTTATCAAGG
GCCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAGAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAATGA
TACGTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGCTCAGAGCGTCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACTATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGTGAAGGGATATCTGATGAAGATATTGAGCATATCTTTGAACGCTTCTATCGTTCAGATAAGGCACGTAACC
GTACATCCACTCAATCTGGTGTAGGTATTGGTTTATCAATTCTTTACCAGATTGTGGAGGCCTACCGATGTCGTATTGAG
GTTAGTTCAGAGCTTGGTGTAGGGACATGTTTCGATTTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

ArlS sensor domain (ArlS_N)

(43-191)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986

Multiple sequence alignment