Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   BSR14_RS07190 Genome accession   NZ_CP018186
Coordinates   1576200..1577426 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain ICDC1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1571200..1582426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS07160 (BSR14_07235) plsY 1571545..1572186 (+) 642 WP_002886068.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  BSR14_RS07165 (BSR14_07240) - 1572304..1572681 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  BSR14_RS07170 (BSR14_07245) - 1572756..1573010 (-) 255 WP_002886199.1 DUF1912 family protein -
  BSR14_RS07175 (BSR14_07250) mmuM 1573123..1574073 (-) 951 WP_045771885.1 homocysteine S-methyltransferase -
  BSR14_RS07180 (BSR14_07255) - 1574085..1575461 (-) 1377 WP_045771886.1 amino acid permease -
  BSR14_RS07185 (BSR14_07260) yihA 1575591..1576190 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  BSR14_RS07190 (BSR14_07265) clpX 1576200..1577426 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  BSR14_RS07195 - 1577444..1577614 (-) 171 WP_002886174.1 hypothetical protein -
  BSR14_RS07200 (BSR14_07270) - 1577619..1578122 (-) 504 WP_045771887.1 dihydrofolate reductase -
  BSR14_RS07205 (BSR14_07275) - 1578230..1579090 (-) 861 WP_045771888.1 thymidylate synthase -
  BSR14_RS07210 (BSR14_07280) - 1579574..1580740 (+) 1167 WP_045771889.1 hydroxymethylglutaryl-CoA synthase -
  BSR14_RS07215 (BSR14_07285) - 1580742..1582016 (+) 1275 WP_045771890.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=206795 BSR14_RS07190 WP_002890340.1 1576200..1577426(-) (clpX) [Streptococcus salivarius strain ICDC1]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=206795 BSR14_RS07190 WP_002890340.1 1576200..1577426(-) (clpX) [Streptococcus salivarius strain ICDC1]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAGACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCGAATATTCTCATGATTGGACCGACTGGTTCAGGGAAGACTTTCCTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACCTCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTG
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGGATTATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATTG
AAGGAACAGTAGCTAGTGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATCCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCTGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGAGTTGAACTTGAGTTTGATCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTTA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGCATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment