Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CNQ49_RS22235 Genome accession   NZ_CP023383
Coordinates   4276570..4277202 (+) Length   210 a.a.
NCBI ID   WP_000242761.1    Uniprot ID   -
Organism   Escherichia coli strain 1223     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4271570..4282202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNQ49_RS22205 (CNQ49_22205) yheS 4271739..4273652 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CNQ49_RS22210 (CNQ49_22210) yheT 4273652..4274674 (+) 1023 WP_000057356.1 hydrolase -
  CNQ49_RS22215 (CNQ49_22215) yheU 4274668..4274886 (+) 219 WP_000907085.1 YheU family protein -
  CNQ49_RS22220 (CNQ49_22220) prkB 4274940..4275809 (+) 870 WP_001274680.1 phosphoribulokinase -
  CNQ49_RS22225 (CNQ49_22225) yhfA 4275864..4276268 (-) 405 WP_001148908.1 OsmC family protein -
  CNQ49_RS22235 (CNQ49_22235) crp 4276570..4277202 (+) 633 WP_000242761.1 cAMP-activated global transcriptional regulator CRP Regulator
  CNQ49_RS22240 (CNQ49_22240) yhfK 4277253..4279343 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CNQ49_RS22245 (CNQ49_22245) argD 4279410..4280630 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CNQ49_RS22250 (CNQ49_22250) pabA 4280716..4281279 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CNQ49_RS22255 (CNQ49_22255) fic 4281311..4281913 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CNQ49_RS22260 (CNQ49_22260) yhfG 4281903..4282070 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23644.41 Da        Isoelectric Point: 8.2710

>NTDB_id=206745 CNQ49_RS22235 WP_000242761.1 4276570..4277202(+) (crp) [Escherichia coli strain 1223]
MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=206745 CNQ49_RS22235 WP_000242761.1 4276570..4277202(+) (crp) [Escherichia coli strain 1223]
ATGGTGCTTGGCAAAACGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

78.049

97.619

0.762
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment