Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BOC72_RS01980 Genome accession   NZ_CP018138
Coordinates   350901..351590 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SP64     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 345901..356590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BOC72_RS01955 (BOC72_00364) gpsB 345998..346339 (+) 342 WP_000200644.1 cell division regulator GpsB -
  BOC72_RS01965 (BOC72_00366) - 346825..347982 (+) 1158 WP_000711398.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  BOC72_RS01970 (BOC72_00367) mapZ 347995..349389 (+) 1395 WP_000039290.1 cell division site-positioning protein MapZ -
  BOC72_RS01975 (BOC72_00368) gndA 349465..350889 (+) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  BOC72_RS01980 (BOC72_00369) covR 350901..351590 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  BOC72_RS01985 (BOC72_00370) cbpC 351688..352650 (+) 963 WP_000698035.1 choline-binding protein CbpC -
  BOC72_RS01990 (BOC72_00371) cbpJ 352669..353667 (+) 999 WP_000771129.1 choline-binding protein CbpJ -
  BOC72_RS01995 (BOC72_00372) - 353785..355017 (-) 1233 WP_000765684.1 MFS transporter -
  BOC72_RS11665 (BOC72_00373) - 355176..355646 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  BOC72_RS11670 - 355546..355904 (-) 359 Protein_369 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=206195 BOC72_RS01980 WP_000518011.1 350901..351590(+) (covR) [Streptococcus pneumoniae strain SP64]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=206195 BOC72_RS01980 WP_000518011.1 350901..351590(+) (covR) [Streptococcus pneumoniae strain SP64]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment