Detailed information NTG0205576

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: YA91_RS20840
• Genome accession: NZ_CP023248
• Coordinates: 2703710..2706283 (-)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus strain MAVP-26
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2698710..2711283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
YA91_RS20840 (YA91_22280)	clpC	2703710..2706283 (-)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator
YA91_RS20845 (YA91_22285)	pgeF	2706431..2707159 (-)	729	WP_005497226.1	peptidoglycan editing factor PgeF	-
YA91_RS20850 (YA91_22290)	rluD	2707161..2708138 (-)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
YA91_RS20855 (YA91_22295)	comL	2708275..2709003 (+)	729	WP_005460312.1	outer membrane protein assembly factor BamD	Machinery gene
YA91_RS20860 (YA91_22300)	-	2709138..2710619 (+)	1482	WP_021447381.1	lytic transglycosylase F	-
YA91_RS20865 (YA91_22305)	raiA	2710950..2711276 (+)	327	WP_005468590.1	ribosome-associated translation inhibitor RaiA	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=205576 YA91_RS20840 WP_005460310.1 2703710..2706283(-) (clpC) [Vibrio parahaemolyticus strain MAVP-26]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=205576 YA91_RS20840 WP_005460310.1 2703710..2706283(-) (clpC) [Vibrio parahaemolyticus strain MAVP-26]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTGGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGTGGTCCTTTAGGGCAACTACTTAAAGAAGTTGGGCTGACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGTCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAGGGCAAATTGGATCCTGTTATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACCAAAAACAACCCAGTGATCATCGGTGAGCCTGGTGTGGGTAAAACCG
CAATTGTGGAAGGCTTGGCGCAGCGAATCGTTAATAACGAAGTGCCAGAAGGTCTACGCGGTCGCCGTGTGCTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCGAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGCTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
AGCTATTCTTCGTGGTCTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATCGATTCAAAACCAGAATCATTGGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAGCACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAGGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGCATGGACATGGAGTTTGCGCGTCGTGCTGGTGATCTAAACCGAATGTCTGAGCTTCAATACGGTCGTATTCC
GGAATTAGAGAAGCAACTAGACTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGCAATAAGGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACCGGCATTCCAGTATCTAAGATGCTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTGCTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCAGTGGTATCGAACGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGCCCAACTGGTGTCGGTAAAACGGAAC
TATGTAAGACACTTGCGAGCTTCATGTTCGACAGTGAAGATGCAATGGTACGTATCGACATGTCGGAGTTCATGGAGAAA
CACTCAGTGGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGTGGTTATCTAACTGAAGCGGTTCG
TCGTAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TTGATGATGGCCGACTCACAGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTCGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGCAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTGGAGGTGTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379