Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   A2U20_RS09730 Genome accession   NZ_CP018032
Coordinates   2019250..2019591 (+) Length   113 a.a.
NCBI ID   WP_021112680.1    Uniprot ID   A0A1T0AD78
Organism   Glaesserella parasuis D74     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2020268..2020453 2019250..2019591 flank 677


Gene organization within MGE regions


Location: 2019250..2020453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2U20_RS09730 (A2U20_09560) comEA/comE1 2019250..2019591 (+) 342 WP_021112680.1 ComEA family DNA-binding protein Machinery gene
  A2U20_RS09735 (A2U20_09565) - 2019691..2020453 (-) 763 Protein_1903 IS5 family transposase -

Sequence

Protein


Download         Length: 113 a.a.        Molecular weight: 12447.29 Da        Isoelectric Point: 9.8973

>NTDB_id=205192 A2U20_RS09730 WP_021112680.1 2019250..2019591(+) (comEA/comE1) [Glaesserella parasuis D74]
MKKLSRYTFSLLFGLFSATTFAEEKVTTSTEHTPVVMQQVAATQKVNANVVNINTATASEIQDKLVGIGAKKAQAIVEYR
EKNGKFLNVEQLTEVSGIGKATLEKNRDRIVIE

Nucleotide


Download         Length: 342 bp        

>NTDB_id=205192 A2U20_RS09730 WP_021112680.1 2019250..2019591(+) (comEA/comE1) [Glaesserella parasuis D74]
ATGAAAAAACTTTCTCGTTACACATTCAGTCTTTTATTTGGGCTTTTCTCTGCAACAACATTTGCTGAAGAAAAAGTAAC
TACGTCAACAGAACATACACCGGTAGTGATGCAACAAGTCGCAGCGACACAAAAAGTAAATGCGAATGTTGTAAATATCA
ATACTGCGACAGCCTCAGAAATCCAAGATAAGTTAGTCGGTATTGGAGCGAAAAAGGCTCAGGCAATTGTGGAATATCGT
GAGAAAAACGGTAAGTTTTTAAATGTTGAGCAGCTCACCGAAGTTTCAGGTATCGGGAAAGCGACACTTGAAAAAAACCG
AGATCGTATTGTGATTGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(46-110)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1T0AD78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

99.115

100

0.991
  comE1/comEA Haemophilus influenzae Rd KW20

59.13

100

0.602

Multiple sequence alignment