Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   BMF34_RS07845 Genome accession   NZ_CP017952
Coordinates   1565140..1567044 (-) Length   634 a.a.
NCBI ID   WP_016356119.1    Uniprot ID   -
Organism   Streptococcus iniae strain 89353     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1560140..1572044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMF34_RS07815 (BMF34_07735) tnpA 1560301..1560687 (+) 387 Protein_1450 IS200/IS605 family transposase -
  BMF34_RS07820 (BMF34_07740) - 1560901..1561257 (-) 357 WP_003101745.1 S1 RNA-binding domain-containing protein -
  BMF34_RS07825 (BMF34_07745) - 1561257..1562657 (-) 1401 WP_003101746.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BMF34_RS07830 (BMF34_07750) - 1562690..1563334 (-) 645 WP_003101747.1 response regulator transcription factor -
  BMF34_RS07835 (BMF34_07755) - 1563327..1564331 (-) 1005 WP_003101748.1 sensor histidine kinase -
  BMF34_RS07840 (BMF34_07760) liaF 1564328..1565023 (-) 696 WP_003101751.1 cell wall-active antibiotics response protein LiaF -
  BMF34_RS07845 (BMF34_07765) pknB 1565140..1567044 (-) 1905 WP_016356119.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BMF34_RS07850 (BMF34_07770) - 1567041..1567781 (-) 741 WP_003101757.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BMF34_RS07855 (BMF34_07775) rsmB 1567819..1569141 (-) 1323 WP_003101760.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BMF34_RS07860 (BMF34_07780) fmt 1569131..1570066 (-) 936 WP_003101762.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 634 a.a.        Molecular weight: 69128.79 Da        Isoelectric Point: 8.9521

>NTDB_id=204347 BMF34_RS07845 WP_016356119.1 1565140..1567044(-) (pknB) [Streptococcus iniae strain 89353]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKTLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIESAT
VAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMVIAQ
SPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMIISA
QDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide


Download         Length: 1905 bp        

>NTDB_id=204347 BMF34_RS07845 WP_016356119.1 1565140..1567044(-) (pknB) [Streptococcus iniae strain 89353]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCCATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAAACCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATGTTAATGGAA
GTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAGAGTGCAACC
GTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGATATTTATGT
TTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACCTTGTTAACA
CCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTTATTGCCCAG
TCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGACACAGTTTT
AATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTAAGCGTGTCA
AAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATTATCAGCGCA
CAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGAAGAACCAAC
AGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCACAAGCAGCT
CATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-248)

PASTA domain (PASTA)

(366-428)

PASTA domain (PASTA)

(435-501)

PASTA domain (PASTA)

(506-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

63.714

92.587

0.59
  stkP/pknB Streptococcus salivarius strain HSISS4

63.589

90.536

0.576
  stkP Streptococcus pneumoniae TIGR4

56.783

81.388

0.462
  stkP Streptococcus pneumoniae D39

56.395

81.388

0.459
  stkP Streptococcus pneumoniae R6

56.395

81.388

0.459
  stkP Streptococcus pneumoniae Rx1

56.202

81.388

0.457

Multiple sequence alignment