Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CGP99_RS06450 Genome accession   NZ_CP022906
Coordinates   1253084..1253857 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 546     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1248084..1258857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP99_RS06430 (CGP99_01163) trmFO 1248428..1249735 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  CGP99_RS06435 (CGP99_01164) xerC 1250152..1251048 (+) 897 WP_115276619.1 tyrosine recombinase XerC -
  CGP99_RS06440 (CGP99_01165) hslV 1251045..1251590 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  CGP99_RS06445 (CGP99_01166) hslU 1251656..1253059 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  CGP99_RS06450 (CGP99_01167) codY 1253084..1253857 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CGP99_RS06455 - 1253908..1254000 (+) 93 WP_001790530.1 hypothetical protein -
  CGP99_RS06460 (CGP99_01168) rpsB 1254199..1254966 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  CGP99_RS06465 - 1255000..1255113 (+) 114 WP_001789890.1 hypothetical protein -
  CGP99_RS06470 (CGP99_01169) tsf 1255148..1256029 (+) 882 WP_000201387.1 translation elongation factor Ts -
  CGP99_RS06475 (CGP99_01170) pyrH 1256166..1256888 (+) 723 WP_000057329.1 UMP kinase -
  CGP99_RS06480 (CGP99_01171) frr 1256907..1257461 (+) 555 WP_001280006.1 ribosome recycling factor -
  CGP99_RS06485 (CGP99_01172) - 1257834..1258604 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=204331 CGP99_RS06450 WP_000055337.1 1253084..1253857(+) (codY) [Staphylococcus aureus strain 546]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=204331 CGP99_RS06450 WP_000055337.1 1253084..1253857(+) (codY) [Staphylococcus aureus strain 546]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment