Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   NCTC11637_00239 Genome accession   LS483488
Coordinates   244996..245733 (+) Length   245 a.a.
NCBI ID   SQJ02315.1    Uniprot ID   -
Organism   Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 239996..250733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NCTC11637_00234 panD 242154..242507 (+) 354 SQJ02287.1 aspartate 1-decarboxylase -
  NCTC11637_00235 - 242510..242812 (+) 303 SQJ02288.1 transcriptional regulatory protein -
  NCTC11637_00236 - 242812..243807 (+) 996 SQJ02289.1 Putative periplasmic protein -
  NCTC11637_00237 comB6 243815..244870 (+) 1056 SQJ02291.1 NADH-ubiquinone oxidoreductase subunit Machinery gene
  NCTC11637_00238 comB7 244886..244999 (+) 114 SQJ02314.1 comB7 putative lipoprotein Machinery gene
  NCTC11637_00239 comB8 244996..245733 (+) 738 SQJ02315.1 ComB1 protein Machinery gene
  NCTC11637_00240 comB9 245733..246713 (+) 981 SQJ02316.1 ComB9 competence protein Machinery gene
  NCTC11637_00241 comB10 246706..247842 (+) 1137 SQJ02317.1 ComB10 competence protein Machinery gene
  NCTC11637_00242 manC 247913..249325 (+) 1413 SQJ02318.1 mannose-1-phosphate guanylyltransferase -
  NCTC11637_00243 gmd 249367..250512 (+) 1146 SQJ02319.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28530.74 Da        Isoelectric Point: 8.9546

>NTDB_id=20397 NCTC11637_00239 SQJ02315.1 244996..245733(+) (comB8) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=20397 NCTC11637_00239 SQJ02315.1 244996..245733(+) (comB8) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAGAGAAACCGATTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCTATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.976

Multiple sequence alignment