Detailed information NTG0020354

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SMA_1184
• Genome accession: HE613569
• Coordinates: 1150566..1151795 (-)
• Length: 409 a.a.
• NCBI ID: CCF02475.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1145566..1156795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_1179	-	1146055..1146507 (+)	453	CCF02470.1	Endonuclease III	-
SMA_1180	-	1146598..1147242 (+)	645	CCF02471.1	Membrane protein, putative	-
SMA_1181	ybgG	1147327..1148274 (-)	948	CCF02472.1	Homocysteine S-methyltransferase	-
SMA_1182	-	1148287..1149663 (-)	1377	CCF02473.1	Amino acid permease	-
SMA_1183	engB	1149962..1150555 (-)	594	CCF02474.1	GTP-binding protein EngB	-
SMA_1184	clpX	1150566..1151795 (-)	1230	CCF02475.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SMA_1185	-	1151828..1151998 (-)	171	CCF02476.1	Hypothetical protein	-
SMA_1186	dhfR	1152015..1152509 (-)	495	CCF02477.1	Dihydrofolate reductase	-
SMA_1187	thyA	1152597..1153436 (-)	840	CCF02478.1	Thymidylate synthase	-
SMA_1188	-	1153758..1154936 (+)	1179	CCF02479.1	Hydroxymethylglutaryl-CoA synthase	-
SMA_1189	mvaA	1154911..1156194 (+)	1284	CCF02480.1	Hydroxymethylglutaryl-CoA reductase	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45154.77 Da
• Isoelectric Point: 4.5644

>NTDB_id=20354 SMA_1184 CCF02475.1 1150566..1151795(-) (clpX) [Streptococcus macedonicus ACA-DC 198]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRITKAAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=20354 SMA_1184 CCF02475.1 1150566..1151795(-) (clpX) [Streptococcus macedonicus ACA-DC 198]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTGAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGCGTGGCTTTATCACAAGAAATTATCAAAGAAGAACTTGCTGAGGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGACCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAATGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCTACAGGTTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCAATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTCTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCCGAACGCGGTATCATTTACGTGGATGAAATTGATAA
AATCGCTAAAAAAGGTGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACCGTTGCTAGCGTACCACCTCAAGGCGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGATACTAAA
AATATCTTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAAGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTGGTCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAAGACATTCAAAAATTTG
GCTTGATTCCAGAGTTTATCGGACGTTTGCCAGTTGTAGCAGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACGCTATTATCATACGACGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGTAAGACAGGAGCTCGTGGTTTACGCTCAATTATTGAAGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACTAAGGTTCGTATCACTAAAGCGGCTGTTGAAGGC
AAAGACAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.976	100	0.9
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575