Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BKP58_RS05955 Genome accession   NZ_CP017763
Coordinates   1063756..1064412 (-) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain 29R7-12     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1058756..1069412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKP58_RS05930 (BKP58_05970) spxH 1058966..1059865 (+) 900 WP_003245184.1 protease adaptor protein SpxH -
  BKP58_RS05940 (BKP58_05980) - 1060180..1060347 (+) 168 WP_003244944.1 hypothetical protein -
  BKP58_RS05945 (BKP58_05985) pepF 1060385..1062214 (-) 1830 WP_173401378.1 oligoendopeptidase F -
  BKP58_RS05950 (BKP58_05990) coiA 1062444..1063565 (-) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  BKP58_RS22655 - 1063639..1063761 (+) 123 WP_003245684.1 hypothetical protein -
  BKP58_RS05955 (BKP58_05995) mecA 1063756..1064412 (-) 657 WP_014479448.1 adaptor protein MecA Regulator
  BKP58_RS22660 - 1064379..1064519 (-) 141 WP_119122854.1 hypothetical protein -
  BKP58_RS05960 (BKP58_06000) yjbE 1064689..1065345 (+) 657 WP_014479447.1 TerC family protein -
  BKP58_RS05965 (BKP58_06005) spx 1065388..1065783 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  BKP58_RS05970 (BKP58_06010) yjbC 1065964..1066542 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  BKP58_RS05975 (BKP58_06015) yjbB 1066706..1067923 (-) 1218 WP_072592593.1 MFS transporter -
  BKP58_RS05980 (BKP58_06020) oppF 1068031..1068948 (-) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=202649 BKP58_RS05955 WP_014479448.1 1063756..1064412(-) (mecA) [Bacillus subtilis strain 29R7-12]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=202649 BKP58_RS05955 WP_014479448.1 1063756..1064412(-) (mecA) [Bacillus subtilis strain 29R7-12]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment