Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPG_0342 Genome accession   CP001015
Coordinates   336111..336800 (+) Length   229 a.a.
NCBI ID   ACF54888.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 331111..341800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_0337 - 331220..331549 (+) 330 ACF55008.1 conserved hypothetical protein -
  SPG_0338 - 331554..331667 (-) 114 ACF55737.1 hypothetical protein -
  SPG_0339 - 332035..333192 (+) 1158 ACF56209.1 conserved hypothetical protein -
  SPG_0340 - 333205..334599 (+) 1395 ACF54841.1 conserved hypothetical protein -
  SPG_0341 gnd 334675..336099 (+) 1425 ACF55311.1 6-phosphogluconate dehydrogenase, decarboxylating -
  SPG_0342 covR 336111..336800 (+) 690 ACF54888.1 RitR response regulator Regulator
  SPG_0343 cbpC 336898..337917 (+) 1020 ACF55634.1 choline-binding protein C -
  SPG_0344 - 338035..339267 (-) 1233 ACF55030.1 conserved hypothetical protein -
  SPG_0345 - 340966..341145 (+) 180 ACF56872.1 conserved domain protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=20178 SPG_0342 ACF54888.1 336111..336800(+) (covR) [Streptococcus pneumoniae G54]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=20178 SPG_0342 ACF54888.1 336111..336800(+) (covR) [Streptococcus pneumoniae G54]
ATGGGGAAACGGATTTTATTACTTGAAAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAACTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment