Detailed information NTG0201763

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: AB525_RS07705
• Genome accession: NZ_CP017685
• Coordinates: 1551931..1552428 (-)
• Length: 165 a.a.
• NCBI ID: WP_001796472.1
• Uniprot ID: A0A5F0HJ55
• Organism: Staphylococcus aureus strain CFSAN007835
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1546931..1557428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB525_RS07680 (AB525_07510)	gcvPB	1547093..1548565 (-)	1473	WP_000202176.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
AB525_RS07685 (AB525_07515)	gcvPA	1548558..1549904 (-)	1347	WP_000019698.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
AB525_RS07690 (AB525_07520)	gcvT	1549924..1551015 (-)	1092	WP_000093344.1	glycine cleavage system aminomethyltransferase GcvT	-
AB525_RS07695 (AB525_07525)	-	1551174..1551698 (-)	525	WP_001015120.1	shikimate kinase	-
AB525_RS07700 (AB525_07530)	-	1551688..1551834 (-)	147	WP_001789879.1	hypothetical protein	-
AB525_RS07705 (AB525_07535)	comGF	1551931..1552428 (-)	498	WP_001796472.1	competence type IV pilus minor pilin ComGF	Machinery gene
AB525_RS07710 (AB525_07540)	comGE	1552346..1552645 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
AB525_RS07715 (AB525_07545)	comGD	1552632..1553078 (-)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
AB525_RS07720 (AB525_07550)	comGC	1553056..1553367 (-)	312	WP_000472255.1	competence type IV pilus major pilin ComGC	Machinery gene
AB525_RS07725 (AB525_07555)	comGB	1553381..1554451 (-)	1071	WP_000776409.1	competence type IV pilus assembly protein ComGB	Machinery gene
AB525_RS07730 (AB525_07560)	comGA	1554423..1555397 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
AB525_RS07735 (AB525_07565)	-	1555449..1556072 (-)	624	WP_001223009.1	MBL fold metallo-hydrolase	-
AB525_RS07740 (AB525_07570)	-	1556069..1556398 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
AB525_RS07745 (AB525_07575)	-	1556398..1557384 (-)	987	WP_000161307.1	ROK family glucokinase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 19169.89 Da
• Isoelectric Point: 10.1358

>NTDB_id=201763 AB525_RS07705 WP_001796472.1 1551931..1552428(-) (comGF) [Staphylococcus aureus strain CFSAN007835]
MILSKVTNKYVPFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDKNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide

• Length: 498 bp

>NTDB_id=201763 AB525_RS07705 WP_001796472.1 1551931..1552428(-) (comGF) [Staphylococcus aureus strain CFSAN007835]
ATGATATTAAGCAAAGTGACCAACAAATATGTGCCATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTTATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGTGTAGATAAAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACAATGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACAATTTATGTATAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (68-155)

• Prokaryotic N-terminal methylation motif (N_methyl) (28-51)

3D structure

• AlphaFold DB: A0A5F0HJ55

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Staphylococcus aureus N315	98.182	100	0.982
comGF	Staphylococcus aureus MW2	95.758	100	0.958