Detailed information NTG0201711

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BSG32_RS04900
• Genome accession: NZ_CP022552
• Coordinates: 963933..966506 (+)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus strain MAVP-R
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 958933..971506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSG32_RS04875 (BSG32_04885)	hpf	958940..959266 (-)	327	WP_005468590.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
BSG32_RS04880 (BSG32_04890)	-	959597..961078 (-)	1482	WP_021450233.1	lytic transglycosylase F	-
BSG32_RS04885 (BSG32_04895)	comL	961213..961941 (-)	729	WP_005460312.1	outer membrane protein assembly factor BamD	Machinery gene
BSG32_RS04890 (BSG32_04900)	rluD	962078..963055 (+)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
BSG32_RS04895 (BSG32_04905)	pgeF	963057..963785 (+)	729	WP_047732495.1	peptidoglycan editing factor PgeF	-
BSG32_RS04900 (BSG32_04910)	clpC	963933..966506 (+)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=201711 BSG32_RS04900 WP_005460310.1 963933..966506(+) (clpC) [Vibrio parahaemolyticus strain MAVP-R]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=201711 BSG32_RS04900 WP_005460310.1 963933..966506(+) (clpC) [Vibrio parahaemolyticus strain MAVP-R]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTGGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGCGGTCCTTTAGGGCAACTACTTAAAGAAGTGGGGCTCACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGTCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAAGGCAAATTGGATCCTGTAATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACCAAAAACAACCCAGTGATCATCGGTGAGCCTGGTGTGGGTAAAACCG
CAATTGTGGAAGGCTTGGCGCAGCGAATTGTTAATAACGAAGTGCCAGAAGGTCTACGCGGTCGCCGTGTTCTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCGAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGCTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
GGCTATTCTTCGTGGTTTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATCGATTCAAAACCAGAATCATTGGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAACACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAGGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGTATGGACATGGAGTTTGCGCGTCGTGCTGGTGATCTGAACCGAATGTCTGAGCTTCAATACGGTCGTATTCC
GGAATTAGAGAAGCAACTAGACTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGCAATAAGGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACCGGCATTCCAGTATCTAAGATGCTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTGCTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCAGTGGTATCGAACGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGCCCAACTGGTGTCGGTAAAACGGAAT
TATGTAAGACACTCGCGAGCTTCATGTTCGACAGCGAAGATGCAATGGTACGTATCGACATGTCGGAGTTCATGGAGAAA
CACTCAGTCGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGTGGTTATCTAACTGAAGCGGTTCG
TCGTAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TCGATGATGGCCGACTCACTGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTCGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGCAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTAGAGGTTTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379