Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CG712_RS02845 Genome accession   NZ_CP022547
Coordinates   540058..540738 (-) Length   226 a.a.
NCBI ID   WP_011226224.1    Uniprot ID   Q5M3P0
Organism   Streptococcus thermophilus strain B59671     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 535058..545738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS02815 (CG712_02840) - 535266..535715 (-) 450 WP_096811543.1 cytidine deaminase family protein -
  CG712_RS02820 (CG712_02845) - 535726..535905 (-) 180 Protein_546 ABC transporter permease -
  CG712_RS02825 (CG712_02850) - 535907..536104 (-) 198 Protein_547 YkgJ family cysteine cluster protein -
  CG712_RS02830 (CG712_02855) - 536189..538189 (-) 2001 WP_096811545.1 ABC transporter permease -
  CG712_RS02835 (CG712_02860) - 538191..538949 (-) 759 WP_011227353.1 ABC transporter ATP-binding protein -
  CG712_RS02840 (CG712_02865) - 539094..540068 (-) 975 WP_011227354.1 sensor histidine kinase -
  CG712_RS02845 (CG712_02870) braR 540058..540738 (-) 681 WP_011226224.1 response regulator transcription factor Regulator
  CG712_RS02850 (CG712_02875) - 541189..541769 (+) 581 Protein_552 xanthine phosphoribosyltransferase -
  CG712_RS10585 (CG712_02880) - 541858..542328 (+) 471 WP_260224116.1 solute carrier family 23 protein -
  CG712_RS10590 - 542352..542795 (+) 444 WP_269768658.1 solute carrier family 23 protein -
  CG712_RS10595 - 542789..543040 (+) 252 WP_011227358.1 solute carrier family 23 protein -
  CG712_RS02860 (CG712_02890) - 543168..544517 (+) 1350 WP_014621757.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26100.45 Da        Isoelectric Point: 4.9992

>NTDB_id=201594 CG712_RS02845 WP_011226224.1 540058..540738(-) (braR) [Streptococcus thermophilus strain B59671]
MHKILLVEDDEVIRQQVKKMLEQWGYEVVLVEDFMEVLSIFVKVEPHLVLMDIGLPLFNGYHWCQEIRKVSKVPIMFLSS
RDQAMDIVMAINMGGDDFVTKPFDQNVLLAKIQGLLRRSYEFGKDQNLLEYMGVILNLKAMDLVYQGEVVSLTKNEFQIL
QVLFDHAGNIVSREDLMKELWNSDFFIDDNTLSVNVARLRKKLEAVGLKDFIETKKGVGYGLRHDG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=201594 CG712_RS02845 WP_011226224.1 540058..540738(-) (braR) [Streptococcus thermophilus strain B59671]
ATGCATAAGATTTTATTAGTTGAGGACGACGAGGTTATCCGTCAACAAGTCAAAAAAATGCTAGAACAGTGGGGTTACGA
AGTTGTTCTTGTTGAAGATTTCATGGAAGTATTATCTATTTTTGTAAAAGTAGAGCCCCACTTGGTTCTTATGGACATTG
GTTTACCTCTATTTAATGGTTATCATTGGTGTCAGGAAATTCGTAAGGTCTCCAAGGTGCCTATTATGTTCTTGTCTTCC
AGAGATCAGGCCATGGATATCGTTATGGCAATCAATATGGGTGGGGACGACTTTGTGACTAAACCCTTTGACCAAAATGT
TCTCTTGGCAAAAATTCAAGGGCTTTTGCGCCGATCTTATGAGTTTGGAAAGGATCAGAATCTTTTGGAATATATGGGTG
TGATTTTGAACCTTAAGGCCATGGATCTGGTTTATCAGGGAGAAGTCGTTTCTTTGACCAAGAACGAGTTTCAGATTTTA
CAAGTTCTCTTCGACCATGCTGGAAATATCGTTAGTCGGGAAGACCTCATGAAGGAGCTTTGGAATAGTGACTTCTTTAT
TGATGATAATACCCTGTCTGTCAATGTGGCACGTTTACGTAAGAAGTTAGAGGCTGTTGGTTTGAAGGACTTTATTGAAA
CCAAGAAAGGTGTCGGTTACGGGTTGCGTCATGATGGATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M3P0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

52.294

96.46

0.504
  micA Streptococcus pneumoniae Cp1015

35.043

100

0.363

Multiple sequence alignment