Detailed information NTG0201594

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: AB478_RS07985
• Genome accession: NZ_CP017679
• Coordinates: 1598080..1598577 (-)
• Length: 165 a.a.
• NCBI ID: WP_001838632.1
• Uniprot ID: A0A6A9GZK7
• Organism: Staphylococcus aureus strain CFSAN007883
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1593080..1603577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB478_RS07960 (AB478_07760)	gcvPB	1593242..1594714 (-)	1473	WP_000202177.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
AB478_RS07965 (AB478_07765)	gcvPA	1594707..1596053 (-)	1347	WP_000019687.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
AB478_RS07970 (AB478_07770)	gcvT	1596073..1597164 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
AB478_RS07975 (AB478_07775)	-	1597323..1597847 (-)	525	WP_001015116.1	shikimate kinase	-
AB478_RS07980 (AB478_07780)	-	1597837..1597983 (-)	147	WP_001789879.1	hypothetical protein	-
AB478_RS07985 (AB478_07785)	comGF	1598080..1598577 (-)	498	WP_001838632.1	competence type IV pilus minor pilin ComGF	Machinery gene
AB478_RS07990 (AB478_07790)	comGE	1598495..1598794 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
AB478_RS07995 (AB478_07795)	comGD	1598781..1599227 (-)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
AB478_RS08000 (AB478_07800)	comGC	1599205..1599516 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
AB478_RS08005 (AB478_07805)	comGB	1599530..1600600 (-)	1071	WP_000776407.1	competence type IV pilus assembly protein ComGB	Machinery gene
AB478_RS08010 (AB478_07810)	comGA	1600572..1601546 (-)	975	WP_000697218.1	competence type IV pilus ATPase ComGA	Machinery gene
AB478_RS08015 (AB478_07815)	-	1601598..1602221 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
AB478_RS08020 (AB478_07820)	-	1602218..1602547 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
AB478_RS08025 (AB478_07825)	-	1602547..1603533 (-)	987	WP_000161315.1	ROK family glucokinase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 19184.87 Da
• Isoelectric Point: 10.2192

>NTDB_id=201594 AB478_RS07985 WP_001838632.1 1598080..1598577(-) (comGF) [Staphylococcus aureus strain CFSAN007883]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNNIENREQRIILHKGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNVQT
KTIYV

Nucleotide

• Length: 498 bp

>NTDB_id=201594 AB478_RS07985 WP_001838632.1 1598080..1598577(-) (comGF) [Staphylococcus aureus strain CFSAN007883]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCTCTCATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGAGTAGATAGAAACAATATTGAAAATAGGGAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACAATGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCCATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATGTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (68-155)

• Prokaryotic N-terminal methylation motif (N_methyl) (28-51)

3D structure

• AlphaFold DB: A0A6A9GZK7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Staphylococcus aureus N315	96.364	100	0.964
comGF	Staphylococcus aureus MW2	96.364	100	0.964